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Asian Journal of Dairy and Food Research, volume 39 issue 3 (september 2020) : 225-231

The Genetic Influence on Sheep Meat Quality, Growth and Body Weight: A Review

Rodica tefania Pelmuþ, Horia Grosu, Mircea Cãtãlin Rotar, Mihail Alexandru Gras, Cristina Lazãr, Florin Popa
1National Research-Development Institute for Animal Biology and Nutrition, Management of Animal Genetic Resources Laboratory, Calea Bucuresti No. 1, 077015, Balotesti, Romania.
Cite article:- Pelmuþ tefania Rodica, Grosu Horia, Rotar Cãtãlin Mircea, Gras Alexandru Mihail, Lazãr Cristina, Popa Florin (2020). The Genetic Influence on Sheep Meat Quality, Growth and Body Weight: A Review. Asian Journal of Dairy and Food Research. 39(3): 225-231. doi: 10.18805/ajdfr.DR-176.

ABSTRACT

Background: Presently, the demand for sheep meat is directed mainly towards high quality products. Meat production improvement and meat quality are very important in sheep industry. The aim of this paper is focusing to review the papers to studies regarding the influence of genes to production and quality of meat.
Methods: Single nucleotide polymorphism microarrays are a molecular genetic method in searching the markers associated with meat production and meat quality traits in animal breeding.
Conclusions: Previous study had shown that genes like myostatin, leptin, calpastatin had influenced the meat production and meat quality traits. The meat production traits and meat quality traits have a moderate heritability and can be included in meat sheep breeding objectives.

REFERENCES

  1. Abousoliman, I., Reyer, H., Oster, M., Maurani, E., Mourad, M., Rashed, M.A.S., Mohamed I., Wimmers K. (2020). Analysis of candidate genes for growth and milk traits in the Egyptian Barki sheep. Animals. 10: 197.
  2. Aali, M., Moradi-Shahrbabak, H., Moradi-Shahrbabak, M., Sadeghi, M., Yousefi, A.R. (2017). Association of the calpastatin genotypes, haplotypes and SNPs with meat quality and fatty acid composition in two Iranian fat and thin tailed sheep breeds. Small Rumin. Res. 149: 40-51.
  3. Al-Mamun, H., Kwan, P., Clark, S.A., Ferdosi, M.H., Tellam, R., Gondro, C. (2015). Genome-wide association study of body weight in Australian Merino sheep reveals an orthologous region on OAR6 to human and bovine genomic regions affecting height and weight. Genetic Selection Evolution. 47(1): 66.
  4. Arora, R., Yadav, H.S., Yadav, D.K. (2014). Identification of novel single nucleotide polymorphisms in candidate genes for mutton quality in Indian sheep. Anim. Mol. Breed. 4: 1-5.
  5. Bagatoli, A., Gasparino, E., Soares, M.A.,M., Amaral, R.M., Macedo, F.A.F., Voltolini, D.M., Del Vesco, A.P. (2013). Expression of calpastatin and myostatin genes associated with lamb meat quality. Genet. Mol. Res. 12(4): 6168-6175.
  6. Bahrami, A., Behzadi, S., Miraei-Ashtiani, S.R., Roh, S.G., Katoh (2013). Genetic polymorphisms and protein structures in growth hormone, growth hormone receptor, ghrelin, insulin-like growth factor 1 and leptin in Mehraban sheep. Gene. 527: 397-404.
  7. Bahrami, A., Miraei-Ashtiani, S.R., Mehrabani-Yeganeh H., Banani-Rad H., Behzadi Sh. (2015). The association between polymorphism of the GH1 gene and changes in protein structure and carcass traits in Mehraban sheep. Animal Production Science. 55: 661-665.
  8. Barendse W. (1995). Muscular hypertrophy gene in Poll Dorset sheep. Project report M.677, Meat Research Corporation, Sydney, Australia.
  9. Barzehkar, R., Salehi, A., Mahjoubi, F. (2009). Polymorhisms of the ovine leptin gene and its association with growth and carcass traits in three Iranian sheep breeds. Iranian Journal of Biotechnology. 7(4): 241-246.
  10. Bolormaa, S., Hayes, B.J., Van der Werf, J.H.J., Pethick, D., Goddend, M.E., Daetwyler, H.D. (2016). Detailed phenotyping identifies genes with pleiotropic effects on body composition. BMC Genomics. 17(1): 224.
  11. Boman, I.A., Klemetsdal, G., Nafstad, O., Blichfeldt, T., Vage, D.I. (2010). Impact of two myostatin (MSTN) mutations on weight gain and lamb carcass classification in Norwegian White Sheep (Ovis aries). Genet. Sel. Evol. 42: 4.
  12. Boucher, D., Swlin, M.F., Castonguay, F., Gariepy, C., Pothier, F. (2006). Detection of polymorphisms in the ovine leptin gene: Association of a single nucleotide polymorphism with muscle growth and meat quality traits. Canadian Journal of Animal Science. 86: 31-35.
  13. Broad, T.E., Glass, B.C., Greer, G.J., Robertson, T.M., Bain, W.E., Lord, E.A., McEwan, J.C. (2000). Search for a locus near to myostatin that increases muscling in Texel sheep in New Zealand. Proc. NZ Soc. Anim. Prod. 60: 110-112.
  14. Cannon, B., Nedergaard, J. (2004). Brown adipose tissue: Function and physiological significance. Physiol. Rev. 84: 277-359.
  15. Clop, A., Mahcy, F., Takeda, H., Pirottin, D., Tordoir, X., Bibe, B., Bouix, J., Caiment, F., Elsen, J.M., Eychenne, F., Larzul, C., Laville, E., Meish, F., Milenkovic, D., Tobin, J., Charlier, C., Georges M.A. (2006). Mutation creating a potential illegitimate micro RNA target site in the myostatin gene affects muscularity in sheep. Nature Genetics. 38: 813-818.
  16. Cockett, N.E., Jackson, S.P., Shay, T.L., Farnir, F., Berghmans, S., Snowder, G.D., Nielson, D., Georges, M. (1996). Polar overdominance at the ovine callipyge locus. Science. 273: 236-238.
  17. Cockett, N.E., Smit, M.A., Bidwell, C.A., Segers, K., Hadfield, T.L., Snowder, G.D., Georges, M., Charlier, C. (2005). The callipyge mutation and other genes that affect muscle hypertrophy in sheep. Genet. Sel. Evol. 37: 65-81.
  18. Depison, Anwar, S., Jamsari, Arnim, Yurnalis (2017). Association of growth hormone gene polymorphism with quantitative characteristics of thin–tailed sheep using PCR-RFLP in Jambi province. African Journal of Biotechnology. 16(20): 1159-1167.
  19. Duckett, S.K., Snowder, G.D., Cockett, N.E. (2000). Effect of the callipyge gene on muscle growth, calpastatin activity and tenderness of three muscles across the growth curve. Journal of Animal Science. 78: 2836-2841.
  20. Freking B.A., Keele J.W., Nielsen M.K., Leymaster K.A. (1998). Evaluation of the ovine callipyge locus: II. Genotypic effects on growth, slaughter and carcass traits. J. Anim. Sci. 76: 2549-2559.
  21. Freking, B.A., Keele, J.W., Shackelford, S.D., Wheeler, T.L., Koohmaraie, M., Nielsen, M.K., Leymaster, K.A. (1999). Evaluation of the ovine callipyge locus: III. Genotypic effects on meat quality. J. Anim. Sci. 77: 2336-2344.
  22. Freking, B.A., Murphy, S.K., Wylie, A.A., Rhodes, S.J., Keele, J.W., Leymaster, K.A., Jirtle, R.L., Smith, T.P. (2002). Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammal’s genome. Res. 10: 1496-1506.
  23. Gan S.Q., Du Z., Liu S.R., Yang Y.L., Shen M., Wang X.H., Yin J.L., Hu X.X., Fei J., Fan J.J., Wang J.H., He Q.H., Zhang Y.S., Li N. Association of SNP haplotypes at the myostatin gene with muscular hypertrophy in sheep. Asian Austral. J. Anim. Sci. 21: 928-935. 
  24. Garza-Hernandez, D., Mucha, S., Banos, G., Kaseja, K., Moore, K., Lambe, N., Yates, J., Bunger, L. (2018). Analysis of single nucleotide polymorphisms variation associated with important economic and computed tomography measured traits in Texel sheep. Animal. 12(5): 915-922.
  25. Gebreselassie, G., Berihulay, H., Jiang, L., Ma, Y. (2020). Review on genomic regions and candidate genes associated with economically important production and reproduction traits in sheep. Animals. 10: 33.
  26. Gholizadeh, M., Rahimi-Mianji, G., Nejati-Javaremi, A. (2015). Genome wide association study of body weight traits in Baluchi sheep. J. Genet. 94: 143-146.
  27. Grochowska, E., Borys, B., Mroczkowski, S. (2020). Effects of intronic SNPs in the myostatin gene on growth and carcass traits in Colored Polish Merino sheep. Genes.11: 2.
  28. Hadjipavlou, G., Matika, O., Clop, A., Bishop, S.C. (2008). Two single nucleotide polymorphisms in the myostatin (GDF8) gene have significant association with muscle depth of commercial Charollais sheep. Animal Genetics. 39: 346-353.
  29. Hajihosseinlo, A., Hashemi, A., Sadeghi, S. (2012). Association between polymorphism in exon 3 of leptin gene and growth traits in the Makooei sheep of Iran. Livestock Research for Rural Development. 24: 9.
  30. Han, J. (2012). Genetic variation in the myostatin gene (MSTN) and its associations with lamb growth and carcass traits in New Zealand Romney sheep, Lincoln University, New Zealand, thesis for Degree of Doctor.
  31. Hickford, J.G.H., Forest, R.H., Zhou, H., Fang, Q., Han, J., Frampton, C.M., Horell, A.L. (2010). Polymorphisms in the ovine myostatin gene (MSTN) and their association with growth and carcass traits in New Zealand Romney sheep. Animals Genetics 41: 64-72.
  32. Hopkins D.L., Fogarty N.M., Mortimer S.I. (2011). Genetic related effects on sheep meat quality. Small Ruminant Research. 101: 160-172.
  33. Hu, Z.L., Park, C.A., Reecy, J.M. (2016). Developmental progress and current status of the Animal QTLdb. Nucleic Acid Research (Database Issue, Advance Acces), doi: 10.1093/nar/gkv 1233.
  34. Jackson, S.P., Green, R.D., Miller, M.F. (1997). Phenotypic characterization of Rambouillet sheep expressing the callipyge gene: I. Inheritance of the condition and production characteristics. J. Anim. Sci. 75:14-18.
  35. Jawasreh, K.I., Al-Amareen, A.H., Aad, P.Y. (2019). Relationships between Hha1 calpastatin gene polymorphism, growth performance and meat characteristics of Awassi sheep. Animals. 9: 667.
  36. Johnson, P.L., McEwan, J.C., Dodds, K.G., Purchas, R.W., Blair, H.T. (2005a). A directed search in the region of GDF8 for quantitative trait loci affecting carcass traits in Texel sheep. J. Anim. Sci. 83: 1988-2000.
  37. Johnson, P.L., McEwan, J.C., Dodds, K.G., Purchas, R.W., Blair, H.T. (2005b). Meat quality traits were unaffected by a quantitative trait locus affecting leg compositions traits in Texel sheep. J. Animal Science. 83:2729-2735.B.
  38. Jonhson, P.L., Dodds, K.G., Bain, W.E., Greer, G.J., McLean, N.J., McLaren, R.J., Galloway, S.M., Van Stijn, T.C., Mc Ewan, J. C. (2009). Investigations into the GDF8 g+6723G-A polymorphism in New Zealand Texel sheep. J. Anim. Sci. 87: 1856-1864.
  39. Karamichou, E., Nute, G.R., Richardson, RI, McLean, K., Bishop, S.C. (2006). A partial genome scan to map quantitative trait loci for carcass composition, as assessed by X-ray computer tomography and meat quality traits in Scottish Blakface Sheep. Anim. Sci. 82:301-309.
  40. Kashani, A., Holman, B.W. B., Malau-Aduli, A.E.O. (2017). Single nucleotide polymorphisms of the ovine ADRB3 gene in Crossbred Australian Sheep supplemented with Spirulina (Arthrospira plantensis) Cyanobacterial Microalgae. Biomed J.Sci and Tech Res. 1:2.
  41. Kawecka, A., Gurgul, A., Miksza-Cybulska, A. (2016). The use of SNP microarrays for biodiversity studies of sheep - A Review. Ann. Anim. Sci. 16(4): 975-987.
  42. Kijas, J.W., McCulloch, R., Hocking Edwards, J.E., Oddy, V.H., Lee, S.H., Van der Werf, J. (2007). Evidence for multiple alleles effecting muscling and fatness at the Ovine GDF8 locus. BMC Genet. 8:80.
  43. Kijas, J.W., Lenstra, J.A., Hayes, B., Boitard, S., Porto Neto, L.R., San Cristobal, M., Servin, B., McCullock, R., Whan, V., Gietzen, K., Paiva, S., Barendse, W, Ciani, E., Raadoma, H., McEwan, J., Dalrymple, B. (2012). Genome wide analysis of the world’s sheep breeds reveals high levels of historic mixture and strong recent selection. PLOS Biology. 10(2): e1001258.
  44. Koohmaraie, M., Shackelford, S.D., Wheeler, T.L., Lonergan, S.M., Doumit, M.E. (1995). A muscle hypertrophy condition in lamb (Callipyge): characterization of effects on muscle growth and meat quality traits. J. Anim. Sci. 73: 3596-3607.
  45. Kumar, S., Meena, A.S., Jyotsana, B., Kumar, R., Naqvi, S.M.K. (2016). Quantitative and qualitative improvement of the sheep mutton production with the help of molecular marker and genom editing tehnology. A review. Bhartiya Krishi Anusandhan Patrika. 31: 285-291.
  46. Laville, E., Bouix, J., Sayd, T., Bibe, B., Elsen, J.M., Larzul, C., Eychenne, F., Maarcq, F., Georges, M. (2004). Effects of a quantitative trait locus for muscle hypertrophy from Belgian Texel sheep on carcass conformation and muscularity. J. Anim. Sci. 82: 3128-3137.
  47. Liebien-Jimenez, Y., Mariezcurrena-Berasain, M.D., De la Fuente, J.L., Abdelfattah, Z.M., Salem Ahmed, E., Kholif, Rocio Vaca-Paulin, Mariezcurrena-Berasain, M.A. (2015). Effect of organic selenium supplementation in the diet of finishing sheep on meat color and pH during shelf life. Indian Journal of Animal Research. 49: 652-657.
  48. Mahrous, K., Hassanane, M., Shafey, H., Mordy, M.A., Rushdi, H. (2016). Association between single nucleotide polymorphism in ovine Calpain gene and growth performance in three Egyptian sheep breeds. J. Genet. Eng. Biotechnol. 14: 233-240.
  49. Matika, O., Riggio, V., Anselme-Moizan, M, Law, A.S., Pong-Wong, R., Archibald, AL., Bishop, S.C. (2016). Genome-wide association reveals QTL for growth, bone and in vivo carcass traits as assessed by computed tomography in Scottish Blackface lambs. Genetics, Selection, Evolution. 48 (1): 11.
  50. McMahon, C., Radcliff, R., Lookingland, K., Tucker, H. (2001) Neuroregulation of growth hormone secretion in domestic animals. Domest. Anim. Endocrinol. 20: 65-87.
  51. Meuwissen, T.H., Hayes, B.J., Goddard, M.E. (2001). Prediction of total genetic value using genome-wide dense marker maps. Genetics 157: 1819-1829.
  52. Mohammadi, H., Shahrebabak, M.M., Sadeghi, M. (2013). Association between single nucleotide polymorphism in the ovine DGAT1 gene and carcass traits in two Iranian sheep breeds. Anim. Biotechnol. 24: 159-167.
  53. Moradian, C., Mohamadi, N., Sheshdeh, S., Hajihosseinlo, A., Ashrfi, F. (2013). Effects of genetic polymorphismat the growth hormone gene on growth traits in Makooei sheep. Eur.J. Exp. Biol. 3: 101-105.
  54. Mortimer, S.I., Van der Werf, J.H.J., Jacob, R.H., Hopkins, D.L., Pannier, L., Pearce, K.L., Gardner, G.E., Warner, R.D., Geesink, G.H., Hocking, Edwards, J.E., Ponnampalam, E.N., Ball, A.J., Gilmour, A.R., Pethick, D.W. (2014). Genetic parameters for meat quality traits of Australian lamb meat. Meat Science 96: 1016-1024.
  55. Naaven, K.S., Jayashankar, M.R., Nagaraja, R., Nagaraja, C.S., Nadeen, F., Satyanarayana, K. (2015). Genetic polymorphism of ovine Calpine gene in Bander sheep. Int. J. Sci. Environ. Technol. 4(3): 804-812.
  56. Nassiry, M.R., Tahmoorespur, M., Javadmanesh, A, Soltani, M., Far, S.F. (2006). Calpastatin polymorphism and its association with daily gain in Kurdi sheep. Iranian Journal of Biotechnology. 4(3).
  57. Nicoll, G.B., Burkin, H.R., Broad, T.E., Jopson, N.B., Greer, G.J., Bain, W.E., Wright C.S., Dodds K.G., Fennessy P.F., McEwan J.C. (1998). Genetic linkage of microsatellite markers to the Carwell locus for rib-eye muscling in sheep. Proc. 6th World Cong. Genet. Appl. Live Prod. 26: 529-533.
  58. Palmer, B.R., Robert, J.G.H., Hickford, G., Bickerstaff, R. (1998). Rapid communication: PCR-RFLP for Mspl and Ncol in the ovine calpastatin gene. J. Anim. Sci. 76: 1449-1500.
  59. Palmer, B.R., Morton, J.D., Roberts, N., Ilian, M.A., Bickerstaffe, R. Marker-assisted selection for meat quality and the ovine calpastatin gene (1999). Proc. Of the New Zealand Soc. Anim. Prod. 59: 266-268.
  60. Pranneth, D.V., Vinoo, R., Sudhakar, K., Jagadeswararao, S., Metta, M. (2020). Genetic polymorphism in a selective intron of ovine myostatin gene and its putative relation with carcass traits in sheep. Agricultural Science Digest. DOI:10.18805/ a.g.D-5081.
  61. Quirino, C.R., Costa, R.L.D., Pacheco, A., Madella-Oliveira, A.F., Beltrame, R. T., Azevedo, A.S., Batholazzi Junior, A., Vega, W.H.O. (2016). Identification of polymorphisms in the myostatin and leptin genes of Santa Ines breed and crossbreed sheep and association with carcass traits. Biosci J., Uberlândia. 32(3): 699-704.
  62. Rovaddoscki, G.A., Pertile, S.F.N., Alvarenga, A.B., Cesar, A.S.M., Pertille, F., Petrini, J., Franzo, V., Soares, W.V.B., Morota G., Spangler, M.L., Pinto, L.F.B., Carvalho, G.G.P., Lanna, D.R.D., Continho, L.L., Mourao, G.B. (2018). Estimates of genomic heritability and genome-wide association study for fatty acids profile in Santa Ines sheep. BMC Genomics. 19: 375.
  63. Riggio, V., Matika, O., Pong-Wong, R, Stear, MJ, Bishop, S.C. (2013). Genome-wide association and regional heritability mapping to identify loci underlying variation in nematode resistance and body weight in Scottish Blackface lambs. Heredity. 110(5): 420-429.
  64. Sadeghi, S., Hajihosseinlo, A., Bohlouli, M. (2014). Haplotype association of ovine leptin gene on breeding value of body measurements in Makooei sheep breed. Biotechnol. Anim. Husb. 30: 233-242.
  65. Safari, E., Fogarty, N.M., Gilmour, A.R. (2005). A review of genetic parameter estimates for wool, growth, meat and reproduction traits in sheep. Livestock Production Science 92: 271-289.
  66. Sahu, A.R., Jeichitra, V., Rajendran, R., Raja, A. (2017). Polymorphism in exon 3 of myostatin (MSTN) gene and its associations with growth traits in Indian sheep breeds. Small Rumin. Res. 149: 81-84.
  67. Shackelford, S.D., Wheeler, T.L., Koohmaraie, M. (1997). Effect of the callipyge phenotype and cooking method on tenderness of several major lamb muscles. J. Anim. Sci. 75: 2100-2105.
  68. Shojaei, M., Abadi, M.M., Fozi, M.A., Dayani, O., Khezri, A., Akhondi, M. (2010). Association of growth trait and leptin gene polymorphism in Kermani sheep. Journal of Cell and Molecular Research. 2: 67-73.
  69. Szkudlarek- Kowalczyk, M., Wisniewska, E., Mroczkowski, S. (2011). Polymorphisms of calpastatin gene in sheep. Journal of Central European Agriculture. 13 (3): 425-432.
  70. Tahmoorespur, M., Valeh, M.V., Nassiry, M.R., Moussavi, A.H., Ansary, M. (2009). Association of the polymorphism in the 5’flanking region of the ovine IGF-I gene with growth traits in the Baluchi sheep. S. Afr. J. Anim. Sci. 39: 97-101.
  71. Trukhachev, V., Skripkin, V., Kvochko, A., Kulichenko, A., Kovalev, D., Pisarenko, S., Volynkina, A., Selionova, M., Aybazov, M., Shumaenko, S., Omarov, A., Mamontova, T., Yatsyk, O., Krivoruchko, A. (2016a). Polymorphism of the IGF1 gene in Russian sheep breed and their influence on some meat production parameters. Slov. Vet. Res. 53 (2): 77-83.
  72. Trukhachev, V., Belyaev, V., Kvochko,A., Kulichenko, A., Kovalev, D., Pisarenko, S., Volynkina, A., Selionova, M., Aybazov, M., Shumaenko, S., Omarov, A., Mamontova, T., Yatsyk, O., Krivoruchko, A., Petrovic, M.P., Pantelic, V., Petrovic, Caro, V. (2016b). MEF2B gene SNP markers of meat productivity in Severokavkazskaya sheep breed. Genetika 48(1): 97-108.
  73. Walling, G.A., Visscher, P.M., Wilson, A.D., McTeir, B.L., Simm, G., Bishop, S.C. (2004). Mapping of quantitative trait loci for growth and carcass traits in commercial sheep populations. J. Anim. Sci. 82: 2234-2245.
  74. Walling, G.A., Visscher, P.M., Simm, G., Bishop, S.C. (2001). Confirmed linkage for qts affecting muscling in Texel sheep on chromosome 2 and 18. Proceedings of the 52nd Annual Meeting of the European Association for Animal Production, 26-29 august 2001, Budapest, G5.6.
  75. Wang, H., Zhang, L., Cao, J., Wu, M., Ma, X., Liu, Z., Liu, R., Zhao, F., Wei, C., Du,L. (2015). Genome-wide specific selection in three domestic sheep breed. PLOS ONE. 10: e0128688.
  76. White, J.D., Vuocolo, T., McDonagh, M., Grounds, M.D., Harper, G.S., Cockett, N.E., Tellam, R. (2008). Analysis of the callipyge phenotype through skeletal muscle development; association of Dlk1 with muscle precursor cells. Differentiation. 76: 283-298.
  77. Wood, J.D., Fisher, A.V., Nute, G.R., Whittington, F.M., Richardson, R.I. (2005). Effects of diets on fatty acids and meat quality. In: Molina Alcaide, E. (ed.), Ben Salem, H., Biala, K., Morand-Fehr, P. Sustainable grazing, nutritional utilization and quality of sheep and goat products. Zaragoza, CIHEAM, 133-141. Options Mediterraneenes: Serie A, Seminaires Mediterraneenes. 67.
  78. Xu, Q., Yan, K.K.F., An, J., Chen, Y. (2008). Characterization of the fast skeletal troponim C (TNNC2) gene in three Chinese native sheep breeds. Arch. Tierzucht. 51: 572-581.
  79. Xu, Q.L., Chen, Y.L., Ma, R.X., Xue, P. (2009). Polymorhism of DGAT1 associated with intramuscular fat-mediated tenderness in sheep. J. Sci. Food Agr. 89: 232-237.
  80. Xu, Q.L., Tang, G.W., Zhang, Q.L., Huang, Y.K., Liu, Y.K., Quan, K., Zhu, K.Y., Zhang, C.X. (2011). The FABP4 gene polymorphismis associated with meat tenderness in three Chinese native sheep breeds. Czech J. Anim. Sci. 56: 1-6.
  81. Xu, H., Zhang, X., Zang, R., Cao, X., Yang, J., Li, J., Lan, X., Wu, J. (2019). Genetic variations in the sheep SIRT7 gene and their correlation with body size traits. Arch. Anim. Breed. 62: 189-197.
  82. Xu, S.S., Li, M.H. (2017). Recent advances in understanding genetic variants associated with economically important traits in sheep (Ovis aries) revealed by high-throughput screening technologies. Front. Agric. Sci. Eng. 4(3): 279-288.
  83. Yang, G., Forrest, R., Zhou, H., Hodge, S., Hickford, J. (2014). Genetic variation in the ovine uncoupling protein 1 gene. Association with carcass traits in New Zealand (NZ) Romney sheep, but no association with growth traits in either NZ Romney or Suffolk sheep. J. Anim. Breed. Genet. 131: 437-444.
  84. Yang, G. (2014). Characterization of genes associated with sheep growth and carcass traits. Lincoln University. PhD Thesis.
  85. Yang, J., Li,W.R., Lv, FH., He, S.G., Tian, S.L., Peng, W.F, Sun, Y.W., Zhao, Y.S.,Tu, XL, Zhang, M, Xie, X.L., Wang, YT., Li, J.Q, Liu, Y.G., Shen, ZQ, Wang, F, Liu, GJ, Lu, H.F., Kantanen, J., Han, J.L., Li, MH, Liu, MJ. (2016). Whole-genome sequencing of native sheep provides insights into rapid adaptations to extreme environments. Molecular Biology and Evolution. 33(10): 2576-2592.
  86. Zhang, L., Liu, J., Zhao, F., Ren, H., Xu, L., Lu, J., Zhang, S., Zhang, X., Wei, C., Lu, G., Zheng, Y., Du, L. (2013). Genome-wide association studies for growth and meat production traits in sheep. PLOS ONE 8(6): e 66569.
  87. Zhang, L., Ma, X., Xuan, J., Wang, H., Yuan, Z., Wu, M., Liu, R., Zhu, C., Wei, C., Zhao, F. (2016). Identification of MEF2B and TRHDE gene polymorphisms related to growth traits in anew Ujumqin sheep population. PLOS ONE. 11: e0159504.
  88. Zhang, L.F., Mousel, M.R., Wu, XL., Michal, JJ, Zhon, X., Ding, B., Dodson, MV, El-Halawany, NK, Lewis, G.S., Jiang, Z. (2013). Genome-wide genetic diversity and differentially selected regions among Suffolk, Rambouillet, Columbia, Polypay and Targhee sheep. PLOS ONE. 8(6): e65942.
  89. Zlobin, A.S., Volkova, N.A, Borodin, P.M., Aksenovich, T.I., Tsepilov, Y.A. (2019). Recent advances in understanding genetic variants associated with growth, carcass and meat productivity traits in sheep (Ovis aries): an update. Arch. Anim. Breed. 62: 579-583.
     
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