<div>The term &lsquo;bio-regulator&rsquo; has been used to encompass the natural and synthetic compounds that regulate various plant growth and developmental processes. Plant bio-regulators (PBRs) previously called plant growth regulators. Use of PBRs with a unique fact finding support assistance from biotechnology made a new approach of manipulating plant biological activities for enhancing growth, yield, quality, nutritive value and an important tool to reduce biotic and abiotic stress in plants. PBRs like jasmonic acid (JA) and its derivatives act as an omnipresent signaling molecules which mediate plant responses to biotic and abiotic stress. Salicylic acid (SA) and methyl salicylate are endogenous signal molecules, also playing pivotal roles in regulating stress responses. A polyamine is low-molecular weight organic compound having two or more primary amino groups, act as ethylene repressor. Prohexodione calcium is a new generation anti-gibberellin. Along with listed names several other bio-regulators are in vogue to improve plant growth, development, stress resistance, pathogenic defense and productivity. In this review, it&rsquo;s an attempt to portray existing advanced knowledge about under utilized bio-regulators role and utility in cultivation of fruit crops.</div>


Advances in Application of Unexploited Plant Bio-regulators for Fruit Production: A Review