In healthy and complicated pregnant cows, on the 2nd and 6th months of pregnancy in order to determine the levels of maternal serum Paraoxonase 1 (PON1) activity and the possibility of complications can occur during the pregnancy might be a premise indication. Serum samples were taken at 2nd and 6th months of 252 pregnant cows at the end of their pregnancies. The cows were classified into two groups such as complicated (Abortion, Dystocia) and non-complicated. Maternal serum PON1 activity in 6th months was lower at complicated group than normally pregnant group (P=0.004; P&lt;0.01), no difference was discovered between these groups in their 2nd month of pregnancy (P&gt;0.05). Among the concentration of HDL, TP and globulin no statistical difference was observed between complicated, subgroups and normal births (P&gt;0.05). Levels of PON1 in 2 and 6 months were statistically different between the groups of dystocia and normal pregnancy (P&lt;0.01; P = 0.003), and abort and normal pregnancy (P&lt;0.05; P=0.033). In this study, it was inferred that the evaluation of PON1 activity early indicator of complications for clinicians that might occur in further periods of pregnancy. These results showed the fact that PON1 activity can be used as a marker relatively at the early phases of pregnancy in complicated cows.&nbsp; 
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Paraoxonase activity an indicator of complications at early stage of complicated pregnant cows

Background: This study was conducted to evaluate the effects of feeding on biochemical parameters in terms of metabolic profile in female and male lambs of Dorper and Lacaune breeds at the developmental stages from birth. 
 
Methods: A total of 32 singleton newborn Dorper and Lacaune breed lambs (n= 8 for each group; male and female) were used. The trial was continued total of 5 nutritional periods each of 21-day after the first two weeks (0-14 days) suckling period. The biochemical parameters determined were paraoxonase 1 (PON1), ischemia modified albumin (IMA), total protein (TP), albumin (ALB), aspartat amino transferase (AST), alanin amino transferase (ALT), alkaline phosphatase (ALP) and malondialdehyde (MDA). 
 
Result: PON1 activity of all lambs was found to be low during the suckling period (P&le;0.001). The highest IMA value was reached in against to the decrease in TP and ALP levels during the weaning period (P&le;0.001). There was no difference between the groups in terms of PON1, TP, ALB and ALP. Increases were observed in the AST, ALT, IMA and MDA levels of male Dorpers. (P&le;0.05). It was concluded that adaptation periods to solid feeds may cause oxidative damage or variable metabolic activity in male Dorpers.

The Effects of Pre-weaning and Post-weaning Feeding Periods on Biochemical Parameters in Terms of Metabolic Profile in Dorper and Lacaune Lambs