<div>Background: Launaea angustifolia (LAN) is a wild plant grown in several Arabian countries in West Asia and North Africa. Launaea is a polymorphic inter- and intraspecific genus that includes about 54 species and 10 subspecies and is classified into eight sections. This study illustrates the effects of Launaea angustifo LAN (LAn) extract on male and female body weight and blood serum enzymes alanine aminotransferase (LAT) and Alkaline phosphatase LAN, with the histology of liver and kidneys used as an animal model for humans. 
 
Methods: A quantity of 100 mg of the extract powder was dissolved in 1 L of DMSO. Experimental rats were divided into five groups with 10 in each group (A, B, C, D, E: 100, 50 and 10 mg/kg and positive control and negative control, respectively).&nbsp;</div>

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Result: No significant differences were observed between the treated and control-group females. However, the mean male body weight showed some variation within the 5th group (E) given the negative control (DMSO) and all treated groups presented lower body weights than the normal control (C). Analysis of the enzymatic activities of (ALT) alanine aminotransferase showed that the females in treatment group A (100 mg) and B (50 mg) had higher levels of ALT than those of group D females (10 mg) at P&lt;0.05 and females in group E at P&lt;0.001). The histology section of the liver and kidney and the histological structure of the rat kidney also showed no differences in all groups. Launaea angustifolia&nbsp;extract (LAn) was found to be safe, especially in the histology of the liver and kidney and for ALT and ALP blood parameters.&nbsp; &nbsp; &nbsp;</div>

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Evaluation of Launaea Angustifolia Extract Treatment on Rat Blood Serum Enzymes and Histology of Liver and Kidney

Background: The purpose of this study is to investigate the effects of Launaea angustifolia methanol extract on the reproductive organs of female rats through the use of chemical screening. 
 
Methods: A total of twenty-five female rats were separated into five distinct groups to be examined. The group that served as the control did not receive any dose, whereas the group that served as the negative control received DEMSO by oral gavage. Group 10 received 10 mg/kg body weight per day, Group 50 received 50 mg/kg body weight per day and Group 100 received 100 mg/kg body weight per day for a period of two weeks. 
 
Result: Despite the fact that the body weights of female rats rose during the course of this investigation, there were no significant variations between the groups after 14 days of dosing occurred. In the case of female rats, the body weights of the control group were found to be considerably greater (P&lt;0.05) in all experimental days, with the exception of day 1 and day 3, when compared to the groups that received 50 and 100 mg. Although there was a discernible rise in the weight of the ovary in the control group in comparison to the group that was exposed to DMSO.

Investigating the Impact of Launaea angustifolia Extract on the Reproduction Function of Female Rats

Background: The aim of this study was characterized to investigate the phytochemical compositions and antibacterial activity of the aerials parts extracts of Launaea arborescens and Limonium sp commonly used in Southeastern Algeria for the treatments of various aliments. 
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Methods: Antibacterial activities were tested against four pathogenic bacteria and fungi such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albican. 
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Result: Ethanolic and aqueous extracts of Limonium sp (40 mg/ml) were highly effective against E. coli with 82 and 85% and 78 and 57% respectively and for chlorid acid extract against Staphylococcus aureus with 84.21% of Limonium sp. The extracted aqueous and methanolic extract of Launaea arborescens at 20 mg/ml were highly effective against E. coli (90% inhibition) and Pseudomonas aeruginosa (64.7% inhibition). Furthermore, the methanol extract of Launaea arborescens had the maximum antibacterial activity against Pseudomonas aeruginosa. For antifungal properties, ethanolic and chlorid acid extracts showed the inhibition activity against fungi tested. The study has shown that Launaea arborescens and Limonium sp are an excellent source of bioactive substances against a wide range of various microbial pathogens. 
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Evaluation of Launaea Angustifolia Extract Treatment on Rat Blood Serum Enzymes and Histology of Liver and Kidney

Investigating the Impact of Launaea angustifolia Extract on the Reproduction Function of Female Rats

Phytochemical Screening and Antibacterial Activity of Extracts of Medicinal Plants of Southwest Algeria