Immunohistochemical Changes of Liver Fasciolosis in Cattle and Sheep in Jeddah, Saudi Arabia

DOI: 10.18805/IJAR.B-1341    | Article Id: B-1341 | Page : 1484-1490
Citation :- Immunohistochemical Changes of Liver Fasciolosis in Cattle and Sheep in Jeddah, Saudi Arabia.Indian Journal of Animal Research.2021.(55):1484-1490
Muslimah Alsulami, Khalil Mohamed khali72@gmail.com
Address : Department of Epidemiology, Faculty of Public Health and Health Informatics, Umm Al-Qura University, Saudi Arabia.
Submitted Date : 19-12-2020
Accepted Date : 1-07-2021


Background: Fasciolosis is a crucial helminthes disease caused by two trematodes of the genus Fasciola: Fasciola hepatica (temperate liver fluke) and Fasciola gigantica (tropical liver fluke).
Methods: A cross-sectional study was conducted on cattle and sheep in a slaughterhouse to detect animals infected with Fasciolosis. Liver samples were collected from infected animals and transferred to the laboratory for histopathological and immunohistochemical examinations.
Result: Microscopically, the liver sections were showed extensive fibrous connective tissue surrounding the central vein and portal area with extensive thickening of bile ducts wall and fibrosis. Marked infiltration of inflammatory cells was also seen.


Biliary cirrhosis Fasciolosis Histopathological Immunohistochemical


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