Loading...

Indian Journal of Animal Research

Immunohistochemical Changes of Liver Fasciolosis in Cattle and Sheep in Jeddah, Saudi Arabia

DOI: 10.18805/IJAR.B-1341    | Article Id: B-1341 | Page : 1484-1490
Citation :- Immunohistochemical Changes of Liver Fasciolosis in Cattle and Sheep in Jeddah, Saudi Arabia.Indian Journal of Animal Research.2021.(55):1484-1490
Muslimah Alsulami, Khalil Mohamed khali72@gmail.com
Address : Department of Epidemiology, Faculty of Public Health and Health Informatics, Umm Al-Qura University, Saudi Arabia.
Submitted Date : 19-12-2020
Accepted Date : 1-07-2021
First Online:

Abstract

Background: Fasciolosis is a crucial helminthes disease caused by two trematodes of the genus Fasciola: Fasciola hepatica (temperate liver fluke) and Fasciola gigantica (tropical liver fluke).
Methods: A cross-sectional study was conducted on cattle and sheep in a slaughterhouse to detect animals infected with Fasciolosis. Liver samples were collected from infected animals and transferred to the laboratory for histopathological and immunohistochemical examinations.
Result: Microscopically, the liver sections were showed extensive fibrous connective tissue surrounding the central vein and portal area with extensive thickening of bile ducts wall and fibrosis. Marked infiltration of inflammatory cells was also seen.

Keywords

Biliary cirrhosis Fasciolosis Histopathological Immunohistochemical

References

  1. Adarosy, H.A., Gad, Y.Z., El-Baz, S.A. and El-Shazly, A.M. (2013). Changing Pattern of Fascioliasis Prevalence Early in the 3rd Millennium in Dakahlia governorate, Egypt: an update. Journal of the Egyptian Society of Parasitology. 240(1412): 1-12.
  2. Aljameel, M.A., Bakhiet, A.O. and Osman, H.M. (2017). Histopathological Characteristics of Liver Fasciolosis in Camels at Nyala Abattoirs (2017). 3rd International Scientific Conference of Camel Research and Production (ISCCRP), Khartoum-Sudan, 21st -23rd November 2017.
  3. Ashrafi, K., Bargues, M.D., O’Neill, S. and Mas-Coma, S. (2014). Fascioliasis: A worldwide parasitic disease of importance in travel medicine. Travel Medicine and Infectious Disease. 12(6): 636-649.
  4. Bancroft, J.D. and Gamble, M. (2008). Theory and Practice of Histological Techniques. Elsevier Health Sciences.
  5. Behairy, B.E., Ehsan, N., Anwer, M., Allam, A., El-Henawy, I., Hameed, N.A. and Zakaria, H.M. (2018). Expression of intrahepatic CD3, CD4 and CD8 T cells in biliary atresia. Clinical and Experimental Hepatology. 4(1): 7.
  6. Degheidy, Nabila S, and Al-Malki, J.S. (2012). Epidemiological studies of fasciolosis in human and animals at Taif, Saudi Arabia. World Appl. Sci. J. 19: 1099-1104.
  7. Degheidy, Nabila, S., Sharaf, E.M. and Al-Malki, J.S. (2013). The incidence of Fasciolasis and some types of bacteria incurred causing lack meat and livers quality of slaughtered animals at Al-Taif, KSA. Assiut. Vet. Med. J. 59(139): 136-141.
  8. El-Hallawany, H.A. and Abdel-Aziz, M.Z. (2012). Clinico-histopathological studies on the correlation between some parasitic infestation on liver and ovarian efficiency in small ruminants. J. Reprod. and Infertility. 3(3): 67-76.
  9. Gordon, H. and Sweets Jr, H.H. (1936). A simple method for the silver impregnation of reticulum. The American Journal of Pathology. 12(4): 545.
  10. Ibrahim, N. (2017). Fascioliasis: systematic review. Advances in Biological Research. 11(5): 278–285.
  11. Labruna, M.B., Costa, F.B., Port-Carvalho, M., Oliveira, A.S., Souza, S.L.P. and Castro, M.B. (2018). Lethal fascioliasis in capybaras (Hydrochoerus hydrochaeris) in Brazil. The Journal of Parasitology, 104(2): 173-176.
  12. Lee, U.E. and Friedman, S.L. (2011). Mechanisms of hepatic fibrogenesis. Best Practice and Research Clinical Gastroenterology. 25(2): 195-206.
  13. Liu, C., Tao, Q., Sun, M., Wu, J. Z., Yang, W., Jian, P. et al. (2010). Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats. Laboratory Investigation. 90(12): 1805-1816.
  14. Mehal, W.Z., Azzaroli, F. and Crispe, I.N. (2001). Immunology of the healthy liver: old questions and new insights. Gastroenterology. 120(1): 250-260.
  15. Mehmood, K., Zhang, H., Sabir, A.J., Abbas, R.Z., Ijaz, M., Durrani, A.Z., et al. (2017). A review on epidemiology, global prevalence and economical losses of fasciolosis in ruminants. Microbial Pathogenesis. 109: 253-262.
  16. Mendes, E. A., Vasconcelos, A.C. and dos Santos Lima, W. (2012). HISTOPATOLOGIA DA INFECÇÃO POR Fasciola hepatica EM Meriones unguiculatus. Revista de Patologia Tropical/Journal of Tropical Pathology, 41(1).
  17. Mendes, R. E., Zafra, R., Pérez-Écija, R.A., Buffoni, L., Martínez- Moreno, Á., Tendler, M. and Pérez, J. (2010). Evaluation of local immune response to Fasciola hepatica experimental infection in the liver and hepatic lymph nodes of goats immunized with Sm14 vaccine antigen. Memorias Do Instituto Oswaldo Cruz. 105(5): 698-705.
  18. Molina, E.C. and Skerratt, L.F. (2005). Cellular and humoral responses in liver of cattle and buffaloes infected with a single dose of Fasciola gigantica. Veterinary Parasitology, 131(1-2): 157-163.
  19. Moreau, E., Hervé, S., Yu, Z.W. and Alain, C. (2002). Modulation of sheep lymphocyte responses by Fasciola hepatica excretory-secretory products. Veterinary Parasitology, 108(3): 207-215.
  20. Najib, M.A., Izani, N.J.N., Amilah, W.A.W.W.N., Faez, A.M. and Shafizol, Z. (2020). A scoping review of the prevalence of fascioliasis in Malaysia and risk factors for infection. The Malaysian Journal of Medical Sciences. 27(1): 22.
  21. Okoye, I.C., Egbu, F.M.I., Ubachukwu, P.O. and Obiezue, N.R. (2015). Liver histopathology in bovine fascioliasis. African Journal of Biotechnology. 14(33): 2576–2582.
  22. Perez, J., de las Mulas, J.M., De Lara, F.C.-M., Gutierrez-Palomino, P.N., Becerra-Martel, C. and Martìnez-Moreno, A. (1998). Immunohistochemical study of the local immune response to Fasciola hepatica in primarily and secondarily infected goats. Veterinary Immunology and Immunopathology. 64(4): 337-348.
  23. Pérez, J., Ortega, J., Moreno, T., Morrondo, P., López-Sández, C., and Martìnez-Moreno, A. (2002). Pathological and immunohistochemical study of the liver and hepatic lymph nodes of sheep chronically reinfected with Fasciola hepatica, with or without triclabendazole treatment. Journal of Comparative Pathology. 127(1): 30-36.
  24. Salmo, N.A.M. (2014). Histopathological study of chronic livers Fascioliasis of cattle in Sulaimani abattoir. AL-Qadisiyah Journal of Veterinary Medicine Sciences. 13(2): 71–80.
  25. Zafra, R., Pérez-Écija, R. A., Buffoni, L., Mendes, R.E., Martínez- Moreno, A., Martínez-Moreno, F.J., et al. (2010). Evaluation of hepatic damage and local immune response in goats immunized with native glutathione S-transferase of Fasciola hepatica. Journal of Comparative Pathology. 143(2-3): 110-119.

Global Footprints