PREVENTIVE EFFECT OF LEUCONOSTOC MESENTEROIDES USED AS PROBIOTIC AGENT IN VIVO

Article Id: ARCC485 | Page : 385 - 388
Citation :- PREVENTIVE EFFECT OF LEUCONOSTOC MESENTEROIDES USED AS PROBIOTIC AGENT IN VIVO.Indian Journal Of Animal Research.2012.(46):385 - 388
A. Rajvanshi*, S. Kulshreshtha,V.K. Nigam1 and R.P. Pareek rajvansh.ankita@gmail.com
Address : Dept. of Biotechnology, Institute of Advance Science &Technology, NIMS University, Jaipur- 302 005, India

Abstract

The preventive effect of Leuconostoc mesenteroides, isolated from cucumber, was studied in vivo. There was a reduction in the count of enterobacteria in mice dosed with Leuconostoc mesenteroides after 3 days of feeding trials. Toxicological data of mice serum revealed that the Leuconostoc isolates had anticholesterolaemic effect. Total serum cholesterol of the mice dosed with Leuconostoc isolate was lower (10.16 mg/dl) than the control. Protection of the gastrointestinal tract (GIT) by this isolate was also observed. Histopathological analysis confirmed that partial protection of the GIT in mice dosed with Leuconostoc isolate and simultaneously infected with Escherichia coli. Thus, isolated L. mesenteroides has a good probiotic effect in terms of reduction of enterobacteria in the GIT, anticholesterolaemic effect and protection of lining of GIT.

Keywords

Probiotic Lactic acid bacteria Leuconostoc Anticholesterolaemic effect .

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