<div>Background: Foot rot is an important contagious disease that causes economic loss in dairy cattle. Even though many antibiotic treatments have been tried on foot rot, very few information about new topical treatment method or product have been reported about the disease. The main objective of this paper is to evaluate an alternative new treatment for foot root disease in dairy cattle. 
 
Methods:&nbsp;Forty-one swap samples were collected from cattle&rsquo;s feet which were further investigated under microscopic examination and polymerase chain reaction (PCR) for Dichelobacter nodosus and Fusobacterium necrophorum. Newly formulated pomade&reg; and ceftiofur hydrochloride (Eficur&reg;) applications were used in foot rot cases. 
 
Result: Polymerized chain reaction revealed D. nodosus in all the samples were as F. necrophorum was seen only in 22 (53.66%) samples. In this study, D. nodosus was considered as the primary agent involved in foot disease of cattle and F. necrophorum along with other bacterias were considered to be associated in the infection. The foot rot wounds formed in all cases (100%) in which D. nodosus, F. necrophorum and other bacteria were detected were healed along with tissue regeneration. As a result of treatment applications, a success rate of 93.33% was obtained in lameness resulting due to medium foot rot cases and 45.45% in severe acute lameness. The lameness recovery rate was found to be 80.48%.</div>

Evaluating the Efficiency of Newly Formulated Pomade&reg; and Ceftiofur Hydrochloride for Treating Foot Rot in Dairy Cattle

<div>Background: The chemical composition and antimicrobial and antioxidant properties of Micromeria congesta (M. congesta) have been previously revealed, but their effect on wound healing has not been investigated. This study aimed to investigate the effects of M. congesta extract in rabbits where full-thickness skin wounds were used.&nbsp; 
 
Methods: Twentyone New Zealand rabbits that were used in the study were divided into 3 groups as Group I (M. congesta&rsquo;s essential oil extract), Group II (Centella asiatica (C. asiatica) extract in pomade form) and Group III (control). Two wounds of 2.8 cm in size were created at the caudal border of the scapula. While the unhealed wound areas were measured on the 7th, 14th, 21st and 28th days.&nbsp; 
 
Result: It was observed histopathologically and immunohistochemically that the healing was more noticeable in Group II in comparison to the others and the wound healing in Group I was more limited. In the genetic analysis, the expression levels of all the target genes in Group I and Group II were significantly higher than those in the control group on the 7th day (p&lt;0.05). The results demonstrate that topical application of the oily form of M. congesta results in significant improvements on wound healing in rabbits.</div>

<div>Investigation of the Effects of Micromeria congesta Essential Oil Extract on Wound Healing in Rabbits and Molecular Genetics Applications</div>