Background: Faecal microbiota transplantation (FMT) is a novel therapy in the field of gastroenterology which has been studied at current times with greater curiosity.&nbsp; 
 
Methods: FMT was applied as an adjunct to symptomatic treatment in Canine Parvovirus (CPV) affected dogs for a period of 8 days once daily from the day of presentation. The results were compared with a similar group suffering from CPV infection maintained only on symptomatic treatment.&nbsp; 
 
Result: Response to FMT was evaluated on the basis of time taken for resolution of diarrhoea, time of hospitalization, scoring of clinical parameters, recurrence of gastroenteritis within 2 months post therapy of the two groups. Furthermore, adverse events and retention time of the transplant after the procedure were noted. It was observed that the 66.67% (4/6) dogs of FMT treated group had a quicker resolution of diarrhoea (mean 48 hours); FMT treated dogs had better clinical scores compared to symptomatic therapy group (score of 1 or clinically insignificant vs 4 or mildly diseased), lesser recurrence of diarrhoea 2 months post therapy in FMT treated group (16.67% vs 50%). Post FMT one case showed low grade fever (n=1) and epistaxis (n=1) respectively which resolved within 24 hours. The mean retention time of the transplant improved from (20.83&plusmn;2.39) minutes to (140&plusmn; 12.66) on Day 7th of the trial (p&lt; 0.01). Faecal Microbiota Transplantation as an adjunct therapy might aid in early resolution of diarrhoea in acute diarrhoea in dogs.

Faecal Microbiota Transplantation in Canine Parvoviral Diarrhoea