Background:&nbsp; Ehrlich ascites carcinoma (EAC) is an undifferentiated carcinoma of the breast that was initially hyperdiploid, 100% malignantand had a short life span. It also had a high transplantability rate, no recurrence and rapid dissemination.&nbsp; 
 
Methods: Therefore, our study designed to assess the potential ameliorative ability of Chia (Salvia hispanica) seeds extract (CSE) on Ehrlich ascites carcinoma (EAC) induced kidney toxicity and tissue damage in mice. Forty female Swiss albino mice in all were split equally into four teams (Gp1, control; Gp2, CSE; Gp3, EAC; Gp4, EAC+CSE).&nbsp; 
 
Result: Current results revealed that; EAC induced elevated in the levels of serum urea, creatinine, potassium ions, chloride ions, renal tissue injury and a significant depletion in serum sodium ions, calcium ions as compared to normal control. In addition to EAC induced variable pathological changes in glomeruli and renal tubules as a marked renal damage, marked degeneration in renal tissues, moderate glomerular atrophyand marked cellular infiltration. Treatment of EAC with CSE (EAC+CSE) improved kidney functions and structure against EAC; where depletion take place in the levels of serum urea, creatinine, potassium ions, chloride ions and elevation in the levels of sodium ions, calcium ions as compared to EAC. One may draw the conclusion that CSE Having the ability to protect the kidneys from EAC cells induced kidney toxicity.

Impact of Chia (Salvia hispanica) Seeds Extract on Ehrlich Ascites Model Induced Kidney Toxicity in Female Mice

Background: Cancer is one of the most dangerous diseases of the twentieth century and the speed of its spread is horrific. It is characterized by cellular growth and invades all tissues of the body. In recent years, all countries of the world have turned to cancer research in order to identify new drugs to treat cancer from various sources , Cancer is the most common disease that causes death in the world and this is attributed to many pathological factors, such as reactive&nbsp; oxygen species, which contribute to the initiation, spread and development of cancer. 
 
Methods: Our current research aims to investigate the therapeutic role of essential oils (C.S.) against Ehrlich Tumor renal damage in Mice. The mice were divided into four group (Gp1, control group, Gp2, Essential oils (C.S) group, Gp3, EAC group, Gp4, EAC with Essential oils (C.S). 
 
Result: Results showed the Essential oils (C.S) in pretreated (G4) lead to an improvement in&nbsp; urea, creatinine levels&nbsp; when compared to the EAC group. Through our results, it was shown that treatment with essential oils (C.S.) improved the levels of urea and creatinine comparing to the Gp3. It was noted that treatment with essential oils (C.S.) improved kidney tissue and VEGF protein expression the Gp4 compared to the Gp3 Groups. It could be concluded that essential oils (C.S) has a possible benefit to the kidneys against EAC induce kidney Toxicity.

Therapeutic Effect of Essential Oils (Citrus sinensis) against Ehrlich Ascites Model Induced Renal Toxicity in Female Mice

Background: Hylocereus Undatus Extract (HUE) It is obtained from the fruit of the white dragon fruit cactus and is rich in antioxidants and vitamin C, Among its benefits are providing environmental protection and reducing the appearance of wrinkles. 
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Methods: Forty female albino mice were divided for fifteen days into four groups: G1: Control , G2: HUE group with a dose of 200 mg/kg/body weight, G3: EAC group, G4:.EAC + HUE Groub, respectively. 
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Result: Our results from the third group showed that mice treated with cancer cells experienced a significant increase in the weight of mice, a increase in both ALT, AST, ALP and a decrease in both Albumin,total protein, as well as damage to liver tissue. When animals infected with cancer cells were treated with an extract of HUE, we observed an increase in the weight of mice, a decrease in both ALT, AST, ALP and an increase in both Albumin,total protein, as well as an improvement in liver tissue.

Impact of Chia (Salvia hispanica) Seeds Extract on Ehrlich Ascites Model Induced Kidney Toxicity in Female Mice

Therapeutic Effect of Essential Oils (Citrus sinensis) against Ehrlich Ascites Model Induced Renal Toxicity in Female Mice

Anticancer Activity of Hylocereus undatus Extract Through in vivo Studies