Background: Sex hormone dermatoses are uncommon in dog and causes overproduction of one or more of the sex hormones or exogenous administration. Ovarian cyst-induced hyperestrogenemia increased cortisol, hypertestosteronemia, and skin lesions mostly underwent undiagnosed and untreated. This case was documented as clinical pathological changes, diagnosis, and treatment of sex hormone imbalance-induced dermatosis due to an ovarian follicular cyst in a Labrador Retriever bitch.

Methods: This clinical investigation was carried out in the month of April&rsquo;2022 at Veterinary Clinical Complex, Veterinary College and Research Institute, Tirunelveli with a history of prolonged proestrus bleeding, perineal pruritus with reddening, swelling, and enlargement of the vulva. Vaginal exfoliative cytology, hormonal assay, ultrasonography, histopathology of skin, and haemato-biochemistry were performed.

Result: Physical examination revealed hyperpigmentation and hyperkeratinization of the skin. Vaginal exfoliative cytology and progesterone assay revealed cytological estrus. Ultrasonography revealed &gt;10 mm-sized anechoic structures in both ovaries along with uterine endometrial hyperplasia. Hormonal analysis revealed hyperestrogenemia and increased cortisol and testosterone. A biopsy of the perineal skin revealed hyperplasia and hyperkeratosis. The case was confirmed as sex hormone imbalance-induced dermatosis due to an ovarian follicular cyst. The animal was treated with two shots of Inj. hCG 500IU in 48 hrs interval followed by OHE after three months.

Successful Management of Follicular Cyst-induced Dermatoses in a Labrador Retriever Dog