Background: Both traditional usage and initial scientific findings suggest that Bunium bulbocastanum, commonly known as Talghouda tuber nut, may offer health benefits, particularly for thyroid dysfunction. This study aims to investigate the therapeutic potential of dietary supplementation in managing pharmacologically thyroid-induced dysfunction and its effects on growth performance and meat quality in rabbits.&nbsp; 
 
Methods: Thirty 45-day-old male Lionhead rabbits were divided into three groups, each with two subgroups. The Control groups received either a standard diet (C) or a diet supplemented with 35% dried Talghouda (Csup). The Hypothyroid group included rabbits induced with hypothyroidism using carbimazole at a dose of 5 mg/kg BW/day (HytCar) and those subsequently treated with dried Talghouda (HytTal). Similarly, hyperthyroid group comprised rabbits induced with hyperthyroidism using levothyroxine (HyrLevo) and those treated with dried Talghouda (HyrTal). Thyroid function was assessed by measuring serum levels of T3, T4 and TSH. Additionally, growth performance and meat quality parameters were evaluated. 
 
Result: Talghouda supplementation significantly influenced thyroid hormone levels in rabbits, elevating T3 and T4 in the hyperthyroid groups (HyrLevo and HyrTal) compared to controls, while suppressing TSH in hyperthyroid groups and elevating it in hypothyroid groups. Talghouda treatment improved growth performance, evidenced by increased weight gain and higher eviscerated carcass weights in the hyperthyroid-treated groups. Meat quality also improved, with favourable pH, dry matter percentage and mineral content observed in the Talghouda-treated hypothyroid group. These findings suggest that Bunium bulbocastanum is a viable natural intervention for managing thyroid dysfunction while maintaining or enhancing growth and meat quality in rabbits, offering promising pharmacological and economic benefits.

Therapeutic Potential of the Algerian Ground Nut (Bunium bulbocastanum) Dietary Supplement in the Treatment of Thyroid-induced Dysfunction and Associated Growth Performance and Meat Quality in Rabbits (Oryctolagus cuniculus)

<div>Background: The species of the Bunium kinds are aromatic plants with medicinal properties. especially the earth nut. which the fruits are used as aroma.and the leaves and roots consumed as vegetables <a href="#taufel_1993">(Taufel et al. 1993)</a>. The present study was conducted in order to valorize its roots by studying the physicochemical and rheological properties of its flour. 
 
Methods: The study focuses on tuber nuts from different regions Khenchela. Mostaganem. Relizane.and Tissemsilet (Algeria).and the earth nut roots harvested the months of February (Y-1 2018 and Y 2019). Those latter were initially reduced into smaller particles. followed by milling into flour using a laboratory mill and sieving through a 250-300 &igrave; aperture screen. The flour samples were packed in resealable polyethylene bags. Mix flour is prepared from wheat flour containing varying proportions of BN flour (1. 2. 5. 10. 15. 20. and 50%). 
 
Result: The results made it possible to conclude that this gluten-free flour (BF) contains about 7% of proteins; lipid and ash contents are 3.34% and 3.96% respectively. On the sensory level. the color parameters (L *, a *, b *) conclude that there is a significant region effect and the harvest period on the color of the flour. The results reveal that all earth-nut flour (EN) differ significantly (P&pound;0.05) in all the chemical properties investigated. The presence of BF improves P when going from 5 to 50% substitution. improves fat rates. However. it has a negative influence on the W energy. the swelling and the P/L ratio of the dough. This study would suggest that earth-nut flour could be suitably incorporated in wheat flour up to 5%, but at higher doses with gluten-free flours. Mean levels of the metals in samples ranged from 62.91 to 80.08 mg/kg with those of Cu and 0.01 mg/kg with those of Pb, Hg.</div>

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Therapeutic Potential of the Algerian Ground Nut (Bunium bulbocastanum) Dietary Supplement in the Treatment of Thyroid-induced Dysfunction and Associated Growth Performance and Meat Quality in Rabbits (Oryctolagus cuniculus)

Physicochemical and Rheological Properties of “Bunium bulbocastanum” Earth-nut Flour