<div>Background: Several single nucleotide polymorphisms had been detected in goats and for the researchers it is important to reveal candidate genes with substantial effects on the traits of economic importance. The aim of this study was to investigate the association between LPL, STAT5 and AGPAT6 gene polymorphisms and milk traits of goats. 
 
Methods: We investigated about 204 goats, four different breeds (Czech White Shorthaired, Saanen, Anglo Nubian, Alpine) and two crossbreeds (Saanen and Alpine, Saanen and Anglo Nubian). The milk samples were analysed using spectrophotometers LactoScope 550 and LactoScope FTIR (Delta Instruments, the Netherlands). The somatic cell count (SCC) in milk was determined by flow cytometry method using the Somascope CA-3A4 (Delta Instruments, the Netherlands). Variations of the goat AGPAT6, STAT5, LPL genes were detected by PCR-RFLP method. 
 
Result: Analysis of AGPAT6 gene revealed that goats with GC genotype had higher milk yield, fat content and lactose content; goats with CG genotype had higher protein content. STAT5 gene analysis showed that goats with CT genotype had higher milk yield; goats with CC genotype had higher fat content and lactose content; goats with TT genotype had higher protein and urea content and also SCC. According to LPL gene analysis, goats with CC genotype had higher milk yield while goats with GG genotype had higher fat and protein content. The highest milk yield was estimated in Saanen and Alpine crossbreed goats while the highest milk fat and protein content was estimated in Anglo Nubian goats.</div>

Gene LPL, STAT5 and AGPAT6 Polymorphisms Relationship with Goat Milk Traits