Commercial Lentils (Lens culinaris) Provide Antioxidative and Broad-spectrum Anti-cancerous Effects

DOI: 10.18805/LR-557    | Article Id: LR-557 | Page : 202-206
Citation :- Commercial Lentils (Lens culinaris) Provide Antioxidative and Broad-spectrum Anti-cancerous Effects.Legume Research-An International Journal.2021.(44):202-206
Sudha Kiran, Joel B. Johnson, Janice S. Mani, Andrew Portman, Trent Mizzi, Mani Naiker d_susiin@yahoo.com
Address : School of Health and Life Sciences, Federation University Australia, Ballarat, VIC, Australia.
Submitted Date : 18-03-2020
Accepted Date : 3-08-2020

Abstract

Background: Interest is growing surrounding functional foods, which provide health benefits in addition to nutritional value. In particular, there is a focus on pulse crops which contain high levels of polyphenolics, such as lentils. 
Methods: In this study, polyphenols were extracted from five L. culinaris varieties and characterized by both their antioxidant profile and cytotoxic activity. 
Result: Hulled varieties had a high content of secondary metabolites (>70 mg GAE/g), while all varieties demonstrated high antioxidant potential (1570-2020 Oxygen Radical Absorbance Capacity index). Furthermore, all extracts showed significant cytotoxicity against H9C2, HepG2, A549 and Calu-1 cancer cell lines. This recommends further investigation into the specific compounds present in L. culinaris, which could potentially be exploited for their anti-cancer activity. 

Keywords

Antioxidant capacity ORAC Polyphenols

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