Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

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Detection of Novel Genes on Recessive Heterozygous Alleles in Pig Breeding: A Review

Hong Thuan Tran, Nguyen Thuy Linh, Thong Minh Le, Thai Van Nam, Anh Phu Nam Bui

ABSTRACT

In this paper, we illustrated several examples of overdominance phenomenon in pigs, in which the selection in favor of lethal genes that generates production traits such as body weight, body condition score and milk yield. We searched the database and literatures on NCBI Databases, Google scholar, Google Web tools. Five novel candidates of Bardet-Biedl Syndrome 9 (BBS9) gene, Transcriptional Adapter-Ada2 (TADA2) gene, RNA Polymerase I subunit B (POLR1B), Ribosome biogenesis homolog (URB1), Polynucleotide kinase 3’-phosphatase (PNKP) are reported to positively affect food intake, cell proliferation. However, embryonic and developmental lethality are displayed in the homozygous recessive individuals. The objective of this review is to show the relationship between genotypes, phenotypes and functions of these novel genes which could benefit pig breeding industry.

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