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Current IssueEditorial BoardOnline First Articles
Indian Journal of
Animal Research
Print ISSN: 0367-6722
Online ISSN: 0976-0555
NASS Rating
6.40
SJR
0.233
CiteScore
0.606

Chief Editor:
M. R. Saseendranath
Kerala Veterinary and Animal Science University, Mannuthy, Thrissur, INDIA
Frequency:Monthly
Indexing:
Science Citation Index Expanded, BIOSIS Preview, ISI Citation Index, Biological Abstracts, Scopus, ...

Research Article

Indian Journal of Animal Research, volume 53 issue 10 (october 2019) : 1316-1320

Increased total antioxidant capacity in renal tissue of female BWF1 mice infected with Plasmodium chabaudi

Mostafa A. Abdel-Maksoud, Fathy A. Abdel-Ghaffar, Azza El-Amir, Gamal Badr, Saleh Al-Quraishy
1<div style="text-align:justify">Zoology Department, College of Science,&nbsp;King Saud University, Riyadh 11451, Saudi Arabia.</div>
Cite article:- Abdel-Maksoud A. Mostafa, Abdel-Ghaffar A. Fathy, El-Amir Azza, Badr Gamal, Al-Quraishy Saleh (2017). Increased total antioxidant capacity in renal tissue of female BWF1 mice infected with Plasmodium chabaudi. Indian Journal of Animal Research. 53(10): 1316-1320. doi: 10.18805/ijar.v0iOF.9115.

ABSTRACT

We have investigated the effect of malaria infection on the urine biochemistry and the renal and hepatic levels of total antioxidant capacity (TAC) in female BWF1 lupus mice. A total of 30 female BWF1 lupus mice were divided into three groups as follows: group (I) control group; group (II) lupus mice infected with live Plasmodium. chabaudi; group (III) lupus mice infected with irradiated P. chabaudi. Mice were killed at day 14 post-infection and plasma samples were collected. live P. chabaudi infection was associated with decreased level of glucose in urine (glucosuria), increased urinary level of both ketones (ketonuria) and blood (hematuria). Additionally, live P. chabaudi infection was associated with increased level of TAC in the renal tissue with decreased level of TAC in the hepatic tissue of infected mice. In conclusion, P. chabaudi infection has a direct effect on the urine biochemistry and the renal and hepatic levels of TAC in BWF1 mice.

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