Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

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  • SJR .282 (2022)

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Effect of nickel toxicity on growth parameters and hepatic enzymes in major carp

Husna Malik, Sumera Sajjad, Sobia Akhtar*, Sana Bilal
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1<p>Department of Zoology, Lahore College for Women University,&nbsp;Lahore. Pakistan</p>
Cite article:- Malik Husna, Sajjad Sumera, Akhtar* Sobia, Bilal Sana (2016). Effect of nickel toxicity on growth parameters and hepaticenzymes in major carp . Indian Journal of Animal Research. 50(3): 370-373. doi: 10.18805/ijar.9591.

Labeo rohita were used to investigate effect of nickel induced toxicity. For this two groups, control groups (N=50) and experimental groups (N=50) were further divided into group 1-4, on the basis of dosage of nickel and blood sampling. Body weight of animals was noted before and after dose treatment. It was found that body length in the experimental group did not show marked increase throughout experimental period while the effect of nickel toxicity was observed on body weight. The weight of experimental fish decreased in experimental group significantly (p<0.05) from first dose to the last dose. Blood plasma was analyzed for biochemical parameters (Total proteins, AST, ALT, and ALP). AST, ALT and ALP levels increased remarkably in experimental fish as compared to the control one, while the levels of total proteins decreased significantly from group 1-4. Results of the present study suggest hepatotoxicity caused by metal and role of nickel as endocrine disrupter in fish body. Nickel also causes changes in growth parameters of animal by affecting their body weight with increased dosage of metal.

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