Therapeutic management of blood transfusion reaction in a crossbred cow

A crossbred cow aged 6 year was presented to Teaching Veterinary Hospital of the Institute with the history of fever, tick infestation, anemia and decreased milk yield since last 10 days. Clinical examination revealed fever, pale mucous membrane and nil rumen motility. Hematological examination findings were anemia, leucopenia, relative neutrophilia and lymphopenia and decreased platelets. Blood smear examination revealed Anaplasma Marginale infection. Animal was treated with blood transfusion, oxytetracyclin, oral hematinic and multivitamin. After half an hour of start of transfusion, cow showed transfusion reaction in the form of urticarial eruptions all over the body, edema of eyelids, lips and over the face, frothy discharge from mouth with muscle tremor and shivering. Transfusion reaction was successfully managed with Adrenalin, Dexona, Avil along with normal saline.