Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

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Indian Journal of Animal Research, volume 35 issue 2 (july to december 2001) : 123 - 125


A.K. Agrawal, S.D. Singh, C. Jayachandran
1Department of Pharmacology and Toxicology, Bihar Veterinary College, Patna-BOO 014, India
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Cite article:- Agrawal A.K., Singh S.D., Jayachandran C. (2023). URINARY DISPOSITION OF AMIKACIN FOLLOWING A SINGLE INTRAVENOUS ADMINISTRATION IN GOATS. Indian Journal of Animal Research. 35(2): 123 - 125. doi: .
The disposition of amikacin in urine was studied after a single intravenous administration @ 10 mg/kg body weight in six healthy goats. The mean concentration of amikacin in the urine samples ranged from 0.24 ± 0.06 to 1037.0 ± 126.7 μg/ml over a period of 30 hours. The peak urine concentration (1037.0 ± 126.7 μg/ml) was recorded at 20 min. The drug appeared in the urine in therapeutic concentration (2 μg/ml) at 2.5 min and the mean therapeutic concentration persisted for 12 hr. Amikacin may be used @ 10 mg/kg intravenously at 12 hr intervals for treating urinary tract infections caused by susceptible bacteria in goats
    1. Arret, B. et. al. (1971). J. Pharma. Sci. 60: 1689-1694.
    2. Baggot. J.D. etal. (1985). Am. J. Vet. Res. 46: 1793-1796.
    3. Brown. M.P. eta/. (1984). Am. J. Vet. Res.45:1610-1613.
    4. Chambers, H. F. and Sande, M.A. (1996). In: Goodman and Gilman's The Pharmacological Basis of Therapeutics (Hardman, J.G. et al. ed.) 9th Edn. Mc. Graw-HilI, New York.
    5. Leroy, A. et a/. (1978). Antibiotic Chemother. 25: 163-180.
    6. Saini, S.PS. and Srivastava, AK (1998). Vet. Res. Commun. 22:59-65.
    7. Tripathi, KD. (1999). In: Essentials of Medical Pharmacology (Tripathi, KD. ed.) 4th Edn. Jaypee Brothers Medical Publishers (P) Ltd., New Delhi.

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