Chief EditorYashpal Singh Malik
Print ISSN 0303-3821
Online ISSN 0976-4631
NAAS Rating 4.95
Influence of subacute exposure of imidacloprid on microelement copper in ovarian tissue of adult female wistar rats
Imidacloprid, a neonicotinoid insecticide is widely and most commonly used insecticide in pest control, seed treatment, termite control and as an ectoparasiticide in veterinary medicine. Its effects on non-target mammals have not been studied extensively. Study to assess its effects on microelement copper in ovarian tissue was carried out in adult female Wistar rats at two dose levels (19 and 38 mg/kg/day) administered orally for 10, 20 and 30 days. Effects were compared with respective control groups administered with 2% gum acacia (1ml/100g b.wt).There was no significant difference observed (p < 0.05) in levels of copper in ovarian tissue at 19 and 38 mg/kg dose of imidacloprid administered orally for 10, 20 and 30 days, respectively. However non significant increase was observed in rats administered with imidacloprid 38 mg/kg for 20 days. Therefore, it is concluded that imidacloprid might alter microelements uptake by ovarian tissue or microelements redistribution within the organs and might affect directly or indirectly the synthesis of reproductive hormones. The results may be used for establishing a biomarker to imidacloprid poisoning/toxicity, and thus may help in differential diagnosis of poisoning or toxicity.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
