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Five male sterile lines of pearl millet were crossed with ten restorer lines. The resultant 50 hybrids were evaluated for different productivity traits such as plant height, days to 50% flowering, productive tillers plant −1, panicle length and grain yield. From these observations, combining ability and heterosis were calculated to select the best performing parents as well as hybrids. Male sterile lines ICMA-95555:: and ICMA-95444 were noticed to be the best general combiner for grain yield and panicle length. The restorer RIB-212S-99 and RIB-1915-99 were identified as good general combiners. Among the crosses, ICMA-95555 x RIB-264S-99, ICMA-95555 x RlB-191S-99, ICMA-95444 x RIB-209S-99, RMS-6A x R1B-204S~99, ICMA-95444 x R1B-208-99 and ICMA-95555 x RlB-212S-99 were recommended for higher grain yield through heterosis breeding. The hybrids produced by different male sterile lines, ICMA-95444 and ICMA-95555 showed also higher heterosis for grain yield which is in tune with the results for general combining ability.