Pathology and molecular genetics of intersexual goats: A review

¹<div style="text-align: justify;">College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, 400 716, China.</div>

ABSTRACT

Intersex traits are serious reproductive disorders in goats, and the intersexual goat can influence development of goat husbandry. In goats, the PIS (polled intersex syndrome) mutation is responsible for both the absence of horns and sex reversal, exclusively affecting XX individuals. PIS is caused by a large deletion of goat chromosome 1q43 that affects the transcription of the genes PISRT1 and FOXL2. Here, we aim to contribute to the discussion on the pathology and molecular genetics of goats’ intersex based on the characteristics of morphology.

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Pathology and molecular genetics of intersexual goats: A review

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