Indian Journal of Animal Research

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Indian Journal of Animal Research, volume 52 issue 7 (july 2018) : 1068-1070

Evaluation of autologous and homologous platelet rich plasma as a surgical wound healing promoter in rabbits

Muhammad Shahid Tahir, Uzma Farid Durrani, Asim Khalid Mahmood, Raheela Akhtar, Rashid Hussain, Abid Hussain, Khizar Matloob, Beenish Zahid
1Pet Centre, University of Veterinary and Animal Sciences, Lahore-54000, Pakistan.
Cite article:- Tahir Shahid Muhammad, Durrani Farid Uzma, Mahmood Khalid Asim, Akhtar Raheela, Hussain Rashid, Hussain Abid, Matloob Khizar, Zahid Beenish (2018). Evaluation of autologous and homologous platelet rich plasma as a surgical wound healing promoter in rabbits. Indian Journal of Animal Research. 52(7): 1068-1070. doi: 10.18805/ijar.B-847.

ABSTRACT

The present study compared the efficacy of autologous and homologous platelet rich plasma (PRP) as a surgical wound healing promoter in rabbits. Sixteen adult healthy rabbits were divided into two groups i.e. A & B. Group A was treated with autologous platelet rich plasma (APRP) and group B was treated with homologous platelet rich plasma (HPRP). Both groups were operated for skin grafting (auto grafting) at two (PRP treated experimental and control) sites. Clinical evaluation of PRP was performed by using macroscopic (edema, exudation, coloration, temperature, cosmetic appearance and healing status) and microscopic (acute inflammation, fibroblast proliferation and granulation tissue proliferation) parameters. The healing status, coloration and cosmetic appearance of APRP treated group were more satisfactory than HPRP treated group. APRP group also showed less inflammation, edema and more granular tissue proliferation as compare to HPRP group. It was concluded that autologous PRP is an efficient surgical wound healing promoter in rabbits.

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