Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 51 issue 6 (december 2017) : 1043-1050

Transcriptome analysis of castrated Bovine reveals the characters of protein accumulation

Xi Wang, Yuanqing Zhang, Xizhong Zhang, Guang Jin, Dongcai Wang, Bo Li, Fang Xu, Lisha Huang, Wenzhong Liu
1<p>College of animal science and veterinary medicine,&nbsp;Shanxi agricultural university, Taigu-030801&nbsp;China</p>
Cite article:- Wang Xi, Zhang Yuanqing, Zhang Xizhong, Jin Guang, Wang Dongcai, Li Bo, Xu Fang, Huang Lisha, Liu Wenzhong (2017). Transcriptome analysis of castrated Bovine reveals the characters of protein accumulation . Indian Journal of Animal Research. 51(6): 1043-1050. doi: 10.18805/ijar.v0iOF.8461.

ABSTRACT

RNA-Seq, a new developing high-throughput sequencing technology in recent years, provides a new and more effective method for research in the genes’ expression. The technology has been used to further improve our understanding on the function of the gene structure information and excavate the new transcripts and new genes. In this study, RNA-seq was employed to study the changes of the proteins after castration in cattle. The results showed the differential expression proteins between castrated cattle and noncastrated cattle were mainly lied in immunity, lipid and fatty acid metabolism and protein synthesis. Through GO and KEGG pathway enrichment analysis, the differential expression proteins were enriched in PPAR pathway which involved in meat quality traits and lipid metabolism and immunity. In addition, the genes were mainly involved in metabolic pathways, such as ECM-receptor, interaction MAPK, signaling pathway PPAR, protein phosphorylation. The function of the proteins involved in castration were not clear and needed further researches.

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