Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 52 issue 5 (may 2018) : 669-673

Teratogenic Effects of Chlorantraniliprole on chick embryos (Gallus gallus domesticus)

Safeer Abbas, Razia Iqbal, Muhammad Zeeshan Butt, Sadaf Niaz, Sumbal Haleem, Sami Ullah, Muhammad Umer, Ali Irfan, Mansour S. Alsaid, Riaz Ullah
1Department of Pharmacgnosy and (Medicinal, Aromatic and Poisonous Plants Research Centre), College of Pharmacy King Saud University Riyadh Saudi Arabia
Cite article:- Abbas Safeer, Iqbal Razia, Butt Zeeshan Muhammad, Niaz Sadaf, Haleem Sumbal, Ullah Sami, Umer Muhammad, Irfan Ali, Alsaid S. Mansour, Ullah Riaz (2017). Teratogenic Effects of Chlorantraniliprole on chick embryos (Gallus gallus domesticus). Indian Journal of Animal Research. 52(5): 669-673. doi: 10.18805/ijar.B-569.

ABSTRACT

The present study was designed to assess the teratogenic effects of Chlorantraniliprole on chick embryos (Gallus gallus domesticus). Different doses of commercial Chlorantraniliprole (0.1, 0.5, 1.0 and 1.5µl/1000µl/egg, in four experimental groups B, C, D, and E respectively) were injected into the yolk sac of eggs before incubation. Embryos were recovered at day 12 of incubation. The mortality rate gradually increased from lower to higher doses. A total of twelve morphometric parameters viz., wet body weight, crown rump length, anterior posterior head diameter, eye diameter, beak length, neck length, humor length, radius and ulna length, metacarpus length, femur length, fibula length and metatarsus length were recorded and compared with control group. These quantitative parameters indicated significant (p<0.05) decreases in all treated groups compared to control group. While the qualitative anomalies such as microcephaly, hydrocephaly, edematous swelling, hematoma formation, abnormal body coloration, microphthalmia, deformed beak, agnathia, micromelia, amelia, omphalocele and ectopia cardis were also observed in treated groups as compared to untreated groups. Therefore it is concluded that Chlorantraniliprole has potentially harmful effects on the development of avian embryos even at very low dose concentration. Hence, due to toxicity of this pesticide it can be used with utmost caution. 

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