Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 51 issue 4 (august 2017) : 654-659

Thermally induced stress revealed behavioral, hormonal and histological disturbances in mice model 

Shahar Bano Memon, Li Lian, Javaid Ali Gadahi, Wang Genlin
1<p>College of Animal Science and Technology,&nbsp;Nanjing Agricultural University, Nanjing 210095, PR China.</p>
Cite article:- Memon Bano Shahar, Lian Li, Gadahi Ali Javaid, Genlin Wang (2016). Thermally induced stress revealed behavioral, hormonaland histological disturbances in mice model . Indian Journal of Animal Research. 51(4): 654-659. doi: 10.18805/ijar.11465.

ABSTRACT

Behavioral, hormonal and histological changes caused by heat stress at 30 and 40oC were studied in mice model. As a result, obnoxious activities like restlessness and hyperactivity were observed. Rectal temperature was significantly increased at 40oC as well as the increase in water intake, whereas, the feed intake remained consistent. Body weight significantly decreased at 40oC. Serum testosterone has shown a decrease in both groups. At day 7 of the treatment, low levels of growth hormone were recorded whereas no significant difference was recorded at day 15. Adrenocorticotropic hormone level was significantly decreased in both groups at day 7. Shrinking of the seminiferous tubules with irregular appearance containing less spermatozoa was also observed at 40oC. Testicular degeneration and atrophy of leydig cells were also observed. Finally, we concluded that heat stress adversely affects the male reproductive functions along with hormonal imbalances and decline in the spermatogenesis. 

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