Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

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Research Article

Indian Journal of Animal Research, volume 50 issue 5 (october 2016) : 764-768

Zinc nanoparticles induced brain lesions and behavioral changes in Tilapia nilotica and Tilapia. zillii

Mohamed Afifi*, Osama A. Abu Zinada, Haytham Ali1, Michel Couderchet2
1<p>Department of Biological Sciences, Faculty of Science,&nbsp;King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.</p>
Cite article:- Afifi* Mohamed, Zinada Abu A. Osama, Ali1 Haytham, Couderchet2 Michel (2016). Zinc nanoparticles induced brain lesions and behavioral changesin Tilapia nilotica and Tilapia. zillii . Indian Journal of Animal Research. 50(5): 764-768. doi: 10.18805/ijar.10269.

ABSTRACT

In this study, the induced behavioral changes and neuropathology of prolonged exposure to high doses of Zinc nanoparticles (Zn-NPs) in two species of tilapia, T. nilotica and T. zilli. was investigated. Fish that were treated with 2000 µg Zn-NPs/L showed severe degenerative changes and vacuolation in the neuropil, particularly of the optic tectum, with congestion of the blood vessels of both the cerebral cortex and the meninx primitive. Loss of the Purkinje cell layer of the cerebellum was noticed as well. Fish showed behavioral changes that included loss of equilibrium, slower movement and swimming sideways. No significant differences (P < 0.05) were observed between T. nilotica and T. zilli in behavioral or pathological changes. The results highlighted the Zn-NPs neurotoxicity and its accompanied neuropathology and related behavioral changes in fish. More caution is needed during the usage of Zn-NPs to avoid possible deleterious impacts on human and animal health.

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