Immunomodulatory Efficiency of Abelmoschus esculentus in Swiss Albino Mice

DOI: 10.18805/ijar.B-3966    | Article Id: B-3966 | Page : 401-406
Citation :- Immunomodulatory Efficiency of Abelmoschus esculentus in Swiss Albino Mice.Indian Journal Of Animal Research.2021.(55):401-406
K.R. Narayanan, P. Dhasarathan, M. Manujula, M. Thenmozhi pdhasarathan@gmail.com
Address : Department of Zoology, Sri Paramakalyani College, Alwarkurichi- 627 412, Tamil Nadu, India.
Submitted Date : 13-12-2019
Accepted Date : 11-08-2020

Abstract

Background: Immunomodulation through natural or synthetic substances may be considered as an alternative for prevention and cure of infections. 
Methods: A total of nineteen groups of Swiss albino mice were experimented for immunological studies with an inclusion of control and immunised control. Lymphocyte count and DTH response in the experimental groups after the administration of plant drugs. The result showed remarkable changes in all kind of treated animals when compared to control. The increment in ‘B’ and “T lymphocyte number was much pronounced in mice by the administration of A. esculentus in combination with immuno-enhansive drug. 
Result: In DTH responses directly correlated with cell mediated immunity and were found to be highest at the maximum dose (100 mg/Kg) of plant extracts A. esculuntus. From the results it was clear that the plant extract induced immunomodulating potential of the test animal. On administration of plant extract an enhanced and visible DTH responses were observed.

Keywords

A. esculentus Immunomodulation Immunological study Swiss albino mice.

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