Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 50 issue 3 (june 2016) : 366-369

A963G single nucleotide variant of BMP15 is not common bio-marker for fecundity in goat

Guang-Xin E, Yong-Fu Huang, Jian-Ning He, Wei-Wei Ni, Yong-Ju Zhao*
1<p>College of Animal Science and Technology, Chongqing Key Laboratory of Forage &amp; Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing 400716, China.</p>
Cite article:- E Guang-Xin, Huang Yong-Fu, He Jian-Ning, Ni Wei-Wei, Zhao* Yong-Ju (2016). A963G single nucleotide variant of BMP15 is not commonbio-marker for fecundity in goat . Indian Journal of Animal Research. 50(3): 366-369. doi: 10.18805/ijar.9363.

ABSTRACT

Bone morphogenetic protein 15 (BMP15) is crucial factor for ovulation as well as for increasing litter size. In the present investigation efforts had been carried out  to assess the genetic variations in Exon 2 region of BMP15 in goat, using polymerase chain reaction single strand conformation polymorphism (PCR-SSCP)  sequencing methods and cooperated frequency distribution to discuss its possibility of related fecundity. Across the 144samples from six breeds were identified in the A963G location of BMP15 using PCR-SSCP and sequences technology. A963A genotype was the most frequent (85.4%) and G963G was the least frequent with a  frequency of 4.2% and A963G is 10.4%.. It  revealed non significant different between high and low fecundity breed. Therefore, this single nucleotide variant is not common Bio-Marker for fecundity in Goat.

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