Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 52 issue 2 (february 2018) : 226-231

Studying the antioxidant role of mushroom against hazards of gamma radiation exposure in male rats

R.G. Hamza, A.N.El Shahat, M.N. Al-seeni
1Food Irradiation Research Department, National Centre for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt.
Cite article:- Hamza R.G., Shahat A.N.El, Al-seeni M.N. (2018). Studying the antioxidant role of mushroom against hazards of gamma radiation exposure in male rats. Indian Journal of Animal Research. 52(2): 226-231. doi: 10.18805/ijar.B-387.

ABSTRACT

This study aimed to investigate the antioxidant role of dried mushroom (DM) against hazards of gamma-irradiation in male rats. In this study, exposure of rats to whole body g-radiation (6 Gy) resulted in hepatic oxidative stress (a significant increase in lipid peroxidation concomitant with a significant decrease in glutathione content and antioxidant enzyme activities); increase liver function enzymes and histopathological disorders. Treatment of irradiated rats with 10% DM significantly improved radiation-induced injury as indicated by the reduction of the indices of liver damage, lipid peroxidation product, the elevation of antioxidants and the attenuation of the tissues histological architecture. These results suggest that oyster mushroom can improve the antioxidant status and minimize the occurrence of oxidative stress- associated disorders.

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