A study of the correlation between Coxiella burnetii seropositivity and abortions in sheep in Eastern and Southeastern Turkey

DOI: 10.18805/ijar.9364    | Article Id: B-380 | Page : 401-405
Citation :- A study of the correlation between Coxiella burnetii seropositivity andabortions in sheep in Eastern and Southeastern Turkey .Indian Journal Of Animal Research.2016.(50):401-405

Ayse Kilic* and Hakan Kalender1 

akilic23@gmail.com
Address :

Department of Microbiology, Sivrice Vocational High School, University of Firat, 23119   Elazig-Turkey.

Submitted Date : 5-10-2015
Accepted Date : 30-01-2016

Abstract

Q fever is a zoonotic disease that occurs worldwide and is caused by the obligate intracellular bacterium Coxiella burnetii. Infected animals are usually asymptomatic, but infection can cause abortion and stillbirth in ruminants. The main purpose of this study was to evaluate prevalance of Coxiella burnetii infection in aborted and nonaborted sheep serum samples in Eastern Anatolia region by using enzyme-linked immunosorbent assay (ELISA). The determine of prevalance in sheep flocks from four provinces (Elazig, Malatya, Tunceli, Bitlis) and tested for anti-C.burnetii antibody detection, by means of Chekit Q fever Elisa kit. 350 serum samples obtained from flocks belonging aborted sheep showed that a total of 56 (16%) were detected seropositivity, whereas 171 serum samples obtained from nonaborted sheep flocks in 13 of the 171 (7.60%) for C.burnetii in seropositivity were observed. Coxiellosis should be considered an important cause of sheep with abortion history and nonaborted in Elazig and neighboring provinces.

Keywords

Abortion C. burnetii; sheep Serology.

References

  1. Aitken, I.D. (1989). Clinical aspects and prevention of Q-fever in animals. Eur. J. Epidemiol. 5: 420-424.
  2. Angelakis, E. and Raoult, D. (2010). Q Fever. Vet. Microbiol. 140:297–309. http: //dx.doi.org/10.1016/j.vetmic.2009.07.016.
  3. Arricau-Bouvery, N., Souriau, A., Lechopier, P., Rodolakis, A. (2003). Experimental Coxiella burnetii infection in pregnant goats: excretion routes. Vet. Res. 34: 423–433.
  4. Arricau-Bouvery, N. and Rodolakis, A. (2005). Is Q fever an emerging or re-emerging zoonosis?. Vet. Res. 36: 327-349.
  5. Berri, M., Souriau, A., Crosby, M., Crochet, D., Lechopier, P., Rodolakis, A. (2001). Relationships between the shedding of Coxiella burnetii, clinical signs and serological responses of 34 sheep. Vet Rec. 148: 502–505.
  6. Berri, M., Souriau, A., Crosby, M., Rodolakis, A. (2002). Shedding of Coxiella burnetii in ewes in two pregnancies following an episode of Coxiella abortion in a sheep flock. Vet. Microbiol. 85: 55–60.
  7. Cabassi, C.S., Taddei, S., Donofrio, G., Ghidini, F., Piancastelli, C., Flammini, C.F., Cavirani, S. (2006). Association between Coxiella burnetii seropositivity and abortion in dairy cattle of Northern Italy. New Microbiol., 
  8. 29: 211-214.
  9. Ceylan, E., Berktas, M., Keles, I., Agaoglu, Z. (2009). Seroprevalance of Q-fever in cattle and sheep in the East of Turkey. Asian J. Anim. Vet. Adv. 4: 114-121. DOI:10.3923/ajava.2009.114.121.
  10. Çekani, M.M., Papa, A., Kota, M., Velo, E., Berxholi, K. (2008). Report of serological study of Coxiella burnetii in domestic animals in Albania. Vet. J. 175: 276-278.
  11. Çetinkaya, B., Kalender, H., Ertas, H.B. (2000). Seroprevalance of Coxiellosis in cattle, sheep and people in the east of Turkey. Vet Rec. 146: 131-136.
  12. Deforge, J.R. and Cone, L.A. (2006). The serologic prevalence of Q-fever (Coxiella burnetii) complement-fixing antibodies in the peninsular bighorn sheep of Southern California. Am. J. Trop. Med. Hyg. 75: 315-317.
  13. Dupuis, G., Peter, O., Mottiez, M.C., Vouilloz, M. (1986). Seroprevalance of human Q fever in Switzerland. Schweiz. Med. Wochenschr. 116: 494-498. 
  14. Fishbein, D.B. and Raoult, D. (1992). A cluster of Coxiella burnetii infections associated with the exposure to vaccinated goats and their unpasturized dairy products. Am. J. Trop. Med. Hyg. 47: 35-40.
  15. Gimenez, D.F. (1964). Staining rickettsiae in yolk sac cultures. Stain. Technol. 30: 135-137.
  16. Guatteo, R., Beaudeau, F., Berri, M., Rodolakis, A., Joly, A., Seegers, H. (2006). Shedding routes of Coxiella burnetii in dairy cows: implications for detection. and control. Vet. Res. 37: 823-833.
  17. Hassig, M. and Lubsen, J. (1998). Relationship between abortions and seroprevalences to selected infectious agents in dairy cows. J. Vet. Med. B. 45: 435–441.
  18. Hilbink, F., Penrose, M., Kovacova, E., Kazar, J. (1993). Q fever is absent from New Zealand. Int. J. Epidemiol. 22: 945-949
  19. Htwe, K.K., Amano, K., Sugiyama, Y., Yagami, K., Minamoto, N., Hashimoto, A., Yamaguchi, T., Fukushi, H., Hirai, K. (1992). Seroepidemiology of Coxiella burnetii in domestic and companion animals in Japan. Vet Rec. 131: 490-490.
  20. Jaspers, U., Thiele, D., Krauss, H. (1994). Monoclonal antibody based competitive ELISA for the detection of specific antibodies against Coxiella burnetii in sera from different animal species. Zentralbl. Bakteriol. 281: 61–66.
  21. Kalender, H. (2001). Elazig ve komþu illerdeki koyunlarda Coxiella burnetii enfeksiyonunun yayginligi. Turk J. Vet. Anim. Sci. 25: 51-55.
  22. Kovacova, E., Kazar, J., Spanelova, D. (1998). Suitability of various Coxiella burnetii antigen preparations for detection of serum antibodies by various tests. Acta Virol. 42: 365-368.
  23. Lang, G.H. (1990). Coxiellosis (Q fever) in animals. In: [Marrie, T.J. (Ed.)], Q fever, the disease. vol.1. CRC Press, Boca Ranton, FL, pp.24-42. 
  24. Lausevic, D. (2001). Prevalance of Coxiella burnetii antibodies in sheep in the territory of Montenegro. Acta Veterinaria. 51: 149-156.
  25. Leloglu, N. (1977). Erzurum, Kars ve Agri Illerinde Q Hummasý Üzerinde Çalismalar. Ankara Üniversitesi Ziraat Fakültesi Dergisi. 8: 113-131.
  26. Little, T.W.A. (1983). Q-Fever-an Enigma. Br. Vet. J. 139: 277-283.
  27. Masala, G., Porcu, R., Sanna, G., Chessa, G., Cillara, G., Chisu, V., Tola, S. (2004). Occurence, Distribution and Role in Abortion of Coxiella burnetii in Sheep and Goats in Sardinia. Italy Veterinary Microbiology. 99: 301-305.
  28. Maurin, M., Raoult, D. (1999). Q Fever. Clin Microbiol Rev. 12: 518-553.
  29. Mcquiston, J.H., Childs, J.E. (2002). Q fever in humans and animals in the United States. Vector Borne Zoonotic Dis. 2: 179-191.
  30. Norlander, L. (2000). Q fever epidemiology and pathogenesis. Microbes. Infect. 2: 417-424.
  31. zdemir, H., Can, R., Sezen, I.Y., Gülcü, H.B., Kalender, H., Basbug, O. (1999). Prevalence of Q fever in sheep in Elazig province and its treatment. Firat Univ. J. Health Sci. 13: 143-149.
  32. Özyer, M., Miroglu, M., Köksal, F. (1990). Çukurova bölgesinde yaþayan insan ve hayvanlarda Q fever infeksiyonu insidansýnýn komplement fiksasyon testi ile araþtýrýlmasý. Pendik Hay. Hast. Merk. Araþt. Enst. Derg. 21: 28-39.
  33. Psaroulaki, A., Hadjichristodoulou, C., Loukaides, F. (2006). Epidemiological study of Q fever in humans, ruminat animals and ticks in Cyprus using a geographical information system. Eur. J. Clin. Microbiol. Infect. Dis. 25: 576-586.
  34. Reimer, L.G. (1993). Q-Fever. Clin. Microbiol Rev. 6: 193-198.
  35. Rodolakis, A. (2006). Q fever, state of art: epidemiology, diagnosis and prophylaxis. Small Ruminant Res. 62: 121–124.
  36. Rousset, E., Durand, B., Berri, M., Dufour, P. (2007). Comparative diagnostic potential of three serological tests for abortive Q fever in goat herds. Vet. Microbiol. 124: 286–297.
  37. Salinas-Melendez, J.A., Avalos-Ramirez, R., Riojas-Valdez, V., Kawas-Garza, J. (2002). Serologic survey in animals of Q fever in Nuevo Leon. Rev. Latinoam Microbiol. 44: 75-78.
  38. Schelling, E., Diguimbaye, C., Daoud, S., Nicolet, J., Boerlin, P., Tanner, M., Zinsstag, J. (2003). Brucellosis and Q-fever seroprevalances of nomadic pastoralists and their livestock in Chad. Prev. Vet. Med. 61: 279-293.
  39. Seyitoglu, S., Özkurt, Z., Dinler, U., Okumus, B. (2006). The Seroprevalence of Coxiellosis in Farmers and Cattle in Erzurum District in Turkey. Turkish Journal of Veterinary and Animal Sciences. 30: 71-75.
  40. Soliman, A.K., Botros, B.A., Watts, D.M. (1992). Evaluation of a competitive immunoassay for detection of Coxiella burnetii antibody in animal sera. J. Clin. Microbiol. 30: 1595–1597.
  41. Tissot Dupont, H. and Raoult, D. (1993). Epidemiologie de la fievre Q. Bull. Epidem. Hebd. 5: 17-18.
  42. Wagner, P., Deutz, A., Fuchs, K., Muller, M., Schuller, W., Kofer, J. (2005). Seroepidemiological study on the spread of Chlamydia psittaci and Coxiella burnetii in Styrian sheep and goat farms. Wiener Tierarztliche Monatsschrift. 92: 114-118. 

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