Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 53 issue 11 (november 2019) : 1436-1439

Expression of Stearoyl Co-enzyme A desaturase (SCD) gene during the juvenile age in layer chicken

N. Govardhana Sagar, T.K. Bhattacharya, A. Rajendra Prasad, Pushpendra Kumar, R.N.Chatterjee, Bharat Bhushan, K.K Kanaka
1Division of Animal Genetics, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly-243 122, Uttar Pradesh, India.
Cite article:- Sagar Govardhana N., Bhattacharya T.K., Prasad Rajendra A., Kumar Pushpendra, R.N.Chatterjee, Bhushan Bharat, Kanaka K.K (2019). Expression of Stearoyl Co-enzyme A desaturase (SCD) gene during the juvenile age in layer chicken. Indian Journal of Animal Research. 53(11): 1436-1439. doi: 10.18805/ijar.B-3698.

ABSTRACT

Stearoyl-CoA desaturase (SCD) is key enzyme in the production of triglycerides and cholesterol. Present study was conducted to know the expression pattern of the Stearoyl-CoA desaturase (SCD) gene in liver during juvenile age (0 day, 14th day, 28th day and 42nd day) in layer birds. Expression of SCD gene increased from the day of hatch to 42nd day, as the body weight and fat deposition increased. The mRNA expression levels of SCD gene during day 0 was differed significantly (P<0.05) with expression levels during other juvenile ages. When compared with SCD expression levels on the day 0 expression levels were up-regulated by 8198.64, 7245.99 and 5587.77 folds over day 14,  28 and  42 respectively. Serum concentration of triglycerides and cholesterol were found to be proportional to the expression levels of SCD gene in liver. It is concluded that SCD expression varied among different age groups during juvenile stages and had significant association with serum triglycerides and cholesterol concentration in layer chicken.

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