Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

  • NAAS Rating 6.50

  • SJR 0.263

  • Impact Factor 0.4 (2024)

Frequency :
Monthly (January, February, March, April, May, June, July, August, September, October, November and December)
Indexing Services :
Science Citation Index Expanded, BIOSIS Preview, ISI Citation Index, Biological Abstracts, Scopus, AGRICOLA, Google Scholar, CrossRef, CAB Abstracting Journals, Chemical Abstracts, Indian Science Abstracts, EBSCO Indexing Services, Index Copernicus
Indian Journal of Animal Research, volume 50 issue 2 (april 2016) : 235-238

Treatment of schistosomiasis by seeds of lagenaria siceraria and its comparison with allopathic drugs in Buffaloes

Sadaf Niaz1, Tanveer Akhter2, Naser M. AbdEl-Salam3, Sultan Ayaz4, Sumaira Shams1, Riaz Ullah, Hidayat Hussain5, M. A. Wasim6
1<p>Department of Chemistry, Government College Ara Khel FR, Kohat, KPK, Pakistan.</p>
Cite article:- Niaz1 Sadaf, Akhter2 Tanveer, AbdEl-Salam3 M. Naser, Ayaz4 Sultan, Shams1 Sumaira, Ullah Riaz, Hussain5 Hidayat, Wasim6 A. M. (2015). Treatment of schistosomiasis by seeds of lagenaria siceraria and its comparison with allopathic drugs in Buffaloes . Indian Journal of Animal Research. 50(2): 235-238. doi: 10.18805/ijar.5959.

A number of antihelmintic drugs are reported for treatment of bovine schistosomiasis. Side effects observed for most of these drugs. The seeds of Lagenaria siceraria were utilized as an alternative for the treatment of Schistosomiasis in buffaloes. It is divided in three groups Group A1 to group A3. A dose of  75, 150 and 225 mg/kg of body weight are given to Group A1 to group A3 respectively. Their effectiveness was weighed against that of Praziquantel at dose intensity of ten mg per Kg of body weight placed as group-B. Effectiveness of “Praziquantel” was found to be hundred per cent after initial dose level. Second dose of the herbal medicines reach up to this mark. The percentage of effectiveness of “Proziquantel” compared with 75mg/kg dose level showed a considerable difference (P<0.01) While other two dose level i.e. “150 mg/kg and 225 mg/kg” did not show any important variation of post treatment. Besides at post cured an important (P<0.001) boost in production of milk “74.58% and 126%” were recorded in sub “group-A3” and “group-B” respectively. Significant increase was noted in feed intake.


  1. Abdel N., Hussain A and Saad MBD, (2008). Prevalence of urinary Schistosomiasis and infection with trematode larval stages in Bulinus truncates from QenaUpper, Egypt J Appl Sci Res,4: 1610-1613.

  2. Aradaib IE and Osburn BI, (1995). Vaccination of cattle against bovine Schistosomosis: current status and future prospects: A review. Preventive Veterinary Medicine, 22: 285-291. 

  3. Atupele P, Tembo K, Steven R, Young S, Dan B, Bowie C and Sarah R, (2009). Prevalence distribution and risk factors for Schistosoma infection among school children in Blantyre, Malawi. PlosNeg Trop Dis, 3: 361-368.

  4. Carlton EJ, Bates MN, Zhong B, Seto EY and Spear RC, (2011). Evaluation of mammalian and intermediate host surveillance methods for detecting Schistosomiasis reemergence in southwest China. PLoSNegl Trop Dis, 5: e987.

  5. Chartier C, Soubirac F, Pors I, Silvestre A, Hubert J, Couquet C and Cabaret J, (2001). Prevalence of antihelmintic resistance in gastrointestinal nematodes of dairy goats under extensive management conditions in southwestern France. J Helminthol, 75: 325–330. 

  6. Da’daraAA, Li YS, XiongT, Zhou J, Williams GM, McManus DP, Feng Z, Yu XL, ary DJ and Harn DA, (2008). DNA-    based vaccines protect against zooneticSchistosomiasisin water buffalo. Parasitol Immunol, 30: 3617-3625.

  7. Doenhoff MJ, Cioli D and Utzinger J, (2008). Praziquantal: mechanism of action, resistance and new derivate for Schistosomiasis. Acta Trop, 108: 175-178.

  8. Hirrose Y, Kirinokiand M andMatsuda H, (2003). Efficacy of administration of praziquantal against Schistosomiasis. Parasitol Int, 52: 141-146.

  9. Hussain A, Khan MN, Iqbal Z and Sajid MS, (2008). An account of the botanical antihelmintics used in traditional veterinary practices in Sahiwal district of Punjab, Pakistan. J Ethnopharmacol, 119: 185–190. 

  10. Jhangir M, Maqbool A, Tanveerand A andMahfooz A, (2003). Therapy of Ancylostomiasis in dogs with Nigella sativa (Kalongi) and Saussurealappa(Qust-e-Shireen). Haryana Vet J India, 40: 48-51. 

  11. Leathwick DM, Pomroy WE and Heath AC, (2001). Antihelmintic resistance in New Zealand. New Zealand Vet J, 49: 227–235.

  12. Maha SFM, Nahla S, El-Shenawy and Shimua EA, (2008). Schistosomamansoni. The Induction of protective immunity against infection in the hamster. Res Vet Sci, 85: 527-533.

  13. Maqbool A, HayatSC and Tanveers A, (2004). Comparative efficacy of various indigenous and allopathic drugs against fasciolosis in buffaloes. Vet Arhiv,74:107-104.

  14. Moskey HE and Harwood PD, (1941). Methods evaluating the efficacy of antihelmintics. Arv J Vet Res, 2: 55-59.

  15. Shah BN, Seth AK and Desai RV, (2010). Phytopharmacological profile of Lagenaria siceraria: A review. Asian journal of Plant Science, 9:152-157.

  16. Soulsby EE, (1982). Helminthes, Arthropods and Protozoa of Domesticated Animals. 7th Ed. ELBS Bailliere Tindall and Cassel, London, pp. 787-792.

  17. Tianping W, Zhang S, Wu W, Zhang G, Lu D, Ornbjeg N and Maria VJ, (2006). Treatment and reinfection of water buffaloes and cattle infected with S. japonicum in Yangtze River valley, Anhui Province, China J Parasitol, 95: 1088-1099.

  18. Vriben N, SilesLM, Lopez-Aban J, Suarez L and Muro A, (2007). The sb 14-3-3-zeta recombinant protein protects against schistosomabovisin mice. Vaccine, 25:4533-4539. 

  19. Waller PJ, Benes G, Thamsborg SM,Sukura A, Richter SH, Ingebrigtsen K, and Hoglund J, (2000). Plants as de-worming agents of livestock in Nordic countries. Acta Vet Scan, 43: 31-44.

  20. Yu-Hua CGW, Hua JF and Yong L, (2006). Experimental observation on the relative side effects of Praziquantal for Schistosmiasis control in cattle and buffaloes. Chinese J Vet Med, 83: 130-135.

Editorial Board

View all (0)