Chief EditorK.M.L. Pathak
Print ISSN 0367-6722
Online ISSN 0976-0555
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Relationship of blood metabolites with reproductive cyclicity in dairy cows
First Online 10-06-2016|
A total of 40 dairy cows in early lactation (60 to 90 days) of four different breeds were selected, comprising 10 animals each from Holstein Friesian (HF), Jersey (J), Achai (ACH) and F1 (HF x Sahiwal). All cows were multiparous with body weight 250-400 kg and milk production ranged from 3 to 12 kg/day. Blood samples were collected from each animal at fortnight intervals for 90 days. In the present study, 65 % of cows reestablished estrus while 35 % cows remained anestrous, 80 % of Holsteins showed estrus followed by 70 % of Jersey and F1 cows while in Achai breed showed only 40 % and 60 % cows remained anestrous. Blood glucose and daily milk yield significantly affected post partum estrus (P<0.01) while serum total protein and triglycerides concentration in blood did not affect post partum estrus. The serum glucose level was lower (39.93 ± 3.14 mg/dl) two months before and showed an increasing trend (49.63 ± 2.47 mg/dl) towards commencement of estrus as well as during estrus (48.20 ± 2.42 mg/dl) and then a declining trend was observed. Mean concentration of serum glucose was significantly higher in Jersey (52.50 ± 2.09 mg/dl) followed by F1 (39.68 ± 1.45 mg/dl), HF (38.85 ± 1.77 mg/dl) and Achai (33.30 ± 2.17 mg/dl) respectively. Breed type significantly affected blood glucose (P < 0.05) in jersey cows whereas both blood glucose and triglycerides were significantly affected (P < 0.001 and P < 0.05, respectively) in F1 cows.
- Abe, N., Lean, I. J., Rabiee, A., Porter, J. and Graham, C. (1994). Effects of sodium monensin on reproductive performance of dairy cattle. II. Effects on metabolites in plasma, resumption of ovarian activity and estrus in lactating cows. Aus. Vet. J. 71:277-282.
- Beareten, H. J. and Fuquary, W. J. (1992). Applied Animal Reproduction. 3rd Ed. Prince Hall, Engleewood Cluffs, New Jersey.
- Bronson, F. H. and Manning, J. M. (1991). The energetic regulation of ovulation: a realistic role for body fat. J. Bio. Repro. 44:945-950.
- Burle, P. M., Mangle, N. S., Kothekhar, M. D. and Kalorey, D. R. (1995). Blood biochemical profiles during various reproductive states of Sahiwal and Jersey X Sahiwal cattle. J. Livestock Adv. 20:13-20.
- Butler, W. R., Everett, R. W. and Coppok, C. E. (1981). The relationships between energy balance, milk production and ovulation in post-partum Holstein cows. J. Ani. Sci. 53:742-748.
- Collard, B. L., Boettcher, P. J., Dekkers, J. C., Petitclerc, D. and Schaeffer, L. R. (2000). Relationships between energy balance and health traits of dairy cattle in early lactation. J. Dairy Sci. 83:2683-2690.
- Coppock, C. E., Noller, C. H. and Wolfe, S. A. (1974). Effect of energy-concentrate ratio in complete feeds fed ad libitum on energy intake in relation to requirements by dairy cows. J. Dairy Sci. 57:1371.
- De Rouen, S. M., Franke, D. E., Morrison, D. G., Yatt, W. E., Coombs, D. F., White, T. W., Humes, P. E. and Greene, B. B. (1994). Prepartum body condition and weight influences on reproductive performance of first-calf beef cows. J. Ani. Sci. 72:1119-1125.
- De Vries, A. and Risco, C. A. (2005). Trends and seasonality of reproductive performance in Florida and Georgia dairy herds from 1976 to 2002. J. Dairy Sci. 88:3155-3165.
- Dematawewa, C. M. and Berger, P. J. (1998). Genetic and phenotypic parameters for 305-day yield, fertility, and survival in Holsteins. J. Dairy Sci. 81:2700-2709.
- Dhuyvetter, D. V. and Caton, J. S. (1996). Manipulation of reproduction and lactation with supplementation in beef cattle. J. Ani. Sci. 47:83-93.
- Folman, Y., Rosenberg, M., Herz, Z. and Davidson, M. (1973). The relationship between plasma progesterone concentration and conception in postpartum dairy cows maintained on two levels of nutrition. J. Repro. Fertility. 34:267.
- Funston, R. N., Roberts, A. J., Hixon, D. L., Halford, D. M., Sanson, D. W. and Moss, G. E. (1995). Effect of acute glucose antagonism on hypophyseal hormones and concentrations of insulin-like growth factor (IGF)-1 and IGF-binding proteins in serum, anterior pituitary, and hypothalamus of ewes. J. Bio. Repro. 52:1179-1186.
- Gutierrez, C. G., Ralph, J. H., Telfer, E. E., Wilmut, I. and Webb, R. (2006). Growth and antrum formation of bovine preantral follicles in long-term culture in vitro. J. Bio. Repro. 62:1322-1328.
- Hansen, L. B. (2000). Consequences of selection for milk yield from a geneticist’s view point. J. Dairy Sci. 83:1145-1150.
- Hewett, C. (1974). Studies on the causes and effect of variation in the blood profile of Swedish dairy cattle. J. Acta Vet. Scand. 50:152-156.
- Horan, B., Mee, J. F., Rath, M., O’Connor, P. and Dillon, P. (2004). The effect of strain of Holstein-Friesian cow and feeding system on reproductive performance in seasonal-calving milk production systems. J. Ani. Sci. 79:453-468.
- Jolly, P. D., McDougall, S., Fitzpatrick, L. A., Macmillan, K. L. and Entwisstle, K. W. (1995). Physiological effects of under nutrition on postpartum anoestrus in cows. J. Repro. Fertility. 49:477-492.
- Jolly, P. D., Mc Sweeney, C. S., Schlink, A. C., Houston, E. M. and Entwistle, K. W. (1996). Reducing post-partum anoestrous interval in first-calf Bos indicus crossbred beef heifers. III. Effect of nutrition on responses to weaning associated variation in metabolic hormone levels. Aust. J. Agri. Res. 47:927-942.
- Keisler, D. H. and Lucy, M. C. (1996). Perception and interpretation of the effects of under nutrition on reproduction. J. Ani. Sci. 74:1-17.
- Kirk, W. G. and George K. Davis. (1970). Blood components of range cattle: phosphorus, calcium, hemoglobin, and hematocrit. J. Range Management. 23:239.
- Koditschek, L. K. and Umbreit, W. W. (1969). J. Bacteriology. 98:1063-1068.
- Lucy, G. B. Martin, Meier, S., Rhodes, F. M., Roche, J. R., Thatcher, W. W. and Webb, R. (2007). New perspectives on the roles of nutrition and metabolic priorities in the subfertility of high-producing dairy cows. J. Dairy Sci. 90:4022-4032.
- Lucy, M. C. (2001). Reproductive loss in high-producing dairy cattle: Where will it end? J. Dairy Sci. 84:1277-1293.
- Lucy, M. C., Staples, C. R., Thatcher, W. W., Erickson, P. S., Cleale, R. M., Firkins, J. L., Murphy, M. R., Clark, J. H. and Brodie, B. O. (1992). Influence of diet composition, dry matter intake, milk production, and energy balance on time of postpartum ovulation and fertility in dairy cows. J. Ani. Prod. 54:323-331.
- Mackle, T. R., Parr, C. R. and Bryant, A. M. (1996). Nitrogen fertilizer effects on milk yield and composition, pasture intake, nitrogen and energy partitioning, and rumen fermentation parameters of dairy cows in early lactation. N. Z. J. Agri. Res. J. 39:341-356.
- Marongiu, M. L., Molle, G., San Juan, L., Bomboi, G., Ligios, C., Sanna, A., Casu, S. and Diskin, M. G. (2002). Effects of feeding level before and after calving, and restricted suckling frequency on postpartum reproductive and productive performance of Sarda and Charolais x Sarda beef cows. J. Live. Prod. Sci. 77:339-348.
- McClure, T. J., Nancarrow, C. D. Radford, H. M. (1978). The effect of 2-deoxy D-glucose on ovarian function of cattle. Aust. J. Biol. Sci. 31:183-186.
- Oldham, G. D. (1984). Protein–energy interrelationships in dairy cows. J. Dairy Sci. 67:1090-1114.
- Park C. S., Fisher, G. R. and Haugse, C. N. (1980). effect of dietry protein and sunflower meal on blood cholesterol of dairy heifers. American J. Dairy Sci. 63:1451-1456.
- Patil, J. S. and Deshpande, B. R. (1979). Changes in body weight, blood glucose and serum proteins in relation to the appearance of post-partum oestrus in Gir cows. J. Repro. Fertility. 57:525.
- Pryce, J. E., Coffey, M. P. and Simm, G. (2001). The relationship between body condition score and reproductive performance. J. Dairy Sci. 84:1508-1515.
- Rabiee, A. R., Lean, I. J., Gooden, J. M. and Miller, B. G. (1999). Relationships among metabolites influencing ovarian function in the dairy cow. J. Dairy Sci. 82:39-44.
- Randel, R. D. (1990). Nutrition and postpartum rebreeding in cattle. J. Ani. Sci. 68:853-862.
- Rasby, R. J., Wettemann, R. P., Harms, P. G., Lusby, K. S. and Wagner, J. J. (1992). GnRH in infundibular stalk-median eminence is related to percentage body fat in carcasses of beef cows. J. Domest. Ani. Endocrinology. 9:71-76.
- Reid, J. T., Me, P. W. and Tyrrell, H. F. (1966). Energy and protein requirements of milk production. J. Dairy Sci. 49:215.
- Richards, M. W., Wettemann, R. P., Shoenemann, H. M. (1989). Nutritional anestrus in beef cows: concentrations of glucose and non-esterified fatty acids in plasma and insulin in serum. J. Ani. Sci. 67:2354-2362.
- Sathish, K. and Sharma, M. C. (1991). Level of hemoglobin and certain serum constituents in rural cows during fertile and non-fertile estrus. Indian Vet. J. 69:361-364.
- Shaffer, L., Roussel, J. D. and Koonce, K. L. (1981). Effect of age, temperature, season and breed on blood characteristics of dairy cattle. J. Dairy Sci. 64:62-70.
- Short, R. E., Bellows, R. A., Staigmiller, R. B., Berardinelli, J. G. and Custer, E. E. (1990). Physiological mechanisms controlling anestrus and infertility in postpartum beef cattle. J. Ani. Sci. 68:799-816.
- Short, R.E. and Adams, D.C. (1988). Nutritional and hormonal interrelationships in beef cattle reproduction. Can. J. Anim. Sci., 68: 29-39
- Slater, R. J. (1986). Experiments in Molecular Biology. Clifton, New Jersey. Humana Press. Page-269.
- SPSS, Inc. (1999). SPSS Regression Models 10.0. Chicago.
- Staples C. R. and Thatcher, W. W. (1990). Relationship between the Early Postpartum Ovarian Activity and Energy Status during Period of High Producing Dairy cows. J. Dairy Sci. 73:938-947.
- Staples, C. R., Burke, J. M. and Thatcher, W. W. (1998). Influence of supplemental fats on reproductive tissues and performance of lactating cows. J. Dairy Sci. 81:856-871.
- Steel, R. G. D. and Torrie, J. H. (1981). Principles and procedures of statistics: A biometrical approach. 2nd. Ed. McGraw- Hill, Singapore.
- Tenhagen, B. A., Vogel, C., Drillich, M., Thiele, G. and Heuwieser, W. (2003). Influence of stage of lactation and milk production on conception rates after timed artificial insemination following estrus synchronization. J. Theriogenology 60:1527-1537.
- Thomas, K. D. and Chaboka, O. (1984). Effect of high protein diets on the hematology and plasma biochemistry of pubertal west African dwarf rams. Vet. Bulletin, 054-06847.
- Trinder, P. A. (1969). Ani. Clinical Biochemistry. 6:24.
- Vohra, S. C., Dindorkar, C. V. and Kaikini. (1995). Studies on blood serum levels of certain biochemical constituents in normal cycling and anestrous crossbred cows. Indian J. Ani. Repro. 16:85-87.
- Wagner, W. C. and Oxenreider, S. L. (1971). Endocrine physiology following parturition. J. Anita. Sci. 32:1.
- Washburn, S. P., Silvia, W. J., Brown, C. H., McDaniel, B. T. and McAllister, A. J. (2002). Trends in reproductive performance in Southeastern Holstein and Jersey DHI herds. J. Dairy Sci. 85:244-251.
- Welch, V. A., R. C. Noble, E. W. Wright, C. Bishop and R. F. Glascock. 1963. The transport in the blood of dietary lipid and its incorporation into milk fat in the cow. J. Biochem. 87:32.
- Wettemann, R. P., Lents, C. A., Ciccioli, N. H., White, F. J. and Rubio, I. (2003). Nutritional and suckling-mediated anovulation in beef cows. J. Ani. Sci. 81:48-59.
- Wright, I. A. and Russel, A. J. F. (1984). Partition of fat, body composition and body condition score in mature cows. J. Ani. Prod. 38:23-32.
- Young, D. S. (2000). Effects of Drugs on Clinical Laboratory Tests, 5th edition, AACC Press, Washington, D.C.
- Zaman, M. S., Ali, C. S. and Ahmed, K. M. (1985). Comparative study of blood glucose, cholesterol, protein and urea content in cyclic, non-cyclic and subestrus lactating buffaloes. Pak. Vet. J. 5:72-75.
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