Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 52 issue 10 (october 2018) : 1413-1415

Novel SNP and Unique Sequences in ATP-binding Cassette Super Family-G Member-2 Transporter (ABCG2) Gene of  Vechur cattle (Bos indicus)

F.A. Lali, K. Anilkumar, T.V. Aravindakshan
1Department of Animal Breeding, Genetics and Biostatistics, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680 651, Kerala, India.
Cite article:- Lali F.A., Anilkumar K., Aravindakshan T.V. (2018). Novel SNP and Unique Sequences in ATP-binding Cassette Super Family-G Member-2 Transporter (ABCG2) Gene of Vechur cattle (Bos indicus). Indian Journal of Animal Research. 52(10): 1413-1415. doi: 10.18805/ijar.B-3399.

ABSTRACT

In the present study, ABCG2 gene of Vechur cattle of Kerala was sequenced and aligned using Basic Local Alignment Search Tool (BLAST) in National Centre for Biotechnology Information (NCBI) site.  The results revealed that ABCG2 gene sequence of Vechur  cattle shows 96% similarity with reference  NCBI sequences.  Addition of eleven base pairs in 13th intron in ABCG2 gene of Vechur cattle which derived a larger amplicon (303 bp) than expected (292 bp).  A novel SNP (G4104A) was identified at 4104th position in intron 13 of ABCG2 gene of Vechur cattle. Further research is suggested to depict the association if any of the novel SNP and unique characters of Vechur cattle.

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