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Novel SNP and Unique Sequences in ATP-binding Cassette Super Family-G Member-2 Transporter (ABCG2) Gene of  Vechur cattle (Bos indicus)

F.A. Lali, K. Anilkumar and T.V. Aravindakshan
Department of Animal Breeding, Genetics and Biostatistics, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680 651, Kerala, India.
lalimagnus@gmail.com

Page Range:
1413-1415
Article ID:
B-3399
Online Published:
1-02-2018
Abstract
In the present study, ABCG2 gene of Vechur cattle of Kerala was sequenced and aligned using Basic Local Alignment Search Tool (BLAST) in National Centre for Biotechnology Information (NCBI) site.  The results revealed that ABCG2 gene sequence of Vechur  cattle shows 96% similarity with reference  NCBI sequences.  Addition of eleven base pairs in 13th intron in ABCG2 gene of Vechur cattle which derived a larger amplicon (303 bp) than expected (292 bp).  A novel SNP (G4104A) was identified at 4104th position in intron 13 of ABCG2 gene of Vechur cattle. Further research is suggested to depict the association if any of the novel SNP and unique characters of Vechur cattle.
Keywords
ABCG2 gene, Novel SNP, Sequence analysis, Vechur cattle.
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