Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 52 issue 2 (february 2018) : 248-253

Effect of varied levels of selenium supplementation in nano form on growth, nutrient intake and digestibility in Wistar albino rats
 

S.J. Bunglavan, A.K. Garg, R.S. Dass, , Sameer Shrivastava
1Division of Animal Nutrition Indian Veterinary Research Institute, Izatnagar-243 122, Bareilly, Uttar Pradesh, India
Cite article:- Bunglavan S.J., Garg A.K., Dass R.S., Shrivastava Sameer (2017). Effect of varied levels of selenium supplementation in nano form on growth, nutrient intake and digestibility in Wistar albino rats. Indian Journal of Animal Research. 52(2): 248-253. doi: 10.18805/ijar.B-3148`.

ABSTRACT

Sixty three weaned male Wistar albino rats (124.3±3.1 g mean body weight) were divided into 9 treatment (T) groups following completely randomized design (CRD) and fed a common basal diet except for selenium (Se) source and levels. While in T1 (control), no Se was supplemented; in T2 and T3, 150 ppb Se was supplemented as nano Se and sodium selenite, respectively. The rats in T4, T5, T6 and T7 were supplemented nano Se at 75, 37.5, 18.75 and 9.375 ppb levels respectively. The rats in T8 and T9 were supplemented 300 ppb Se as nano Se and sodium selenite respectively.  The experimental feeding lasted for a period of 13 weeks including a digestion trial of 5 days after 40 days of experimental feeding. The intake and digestibility of DM, OM, EE, CF, NFE and CP were similar (P>0.05) among different treatment groups, however CP digestibility was significantly (P<0.05) higher in T3 supplemented with 150 ppb nano Se. The intake and apparent absorption of Calcium (Ca) and Phosphorus (P) were similar (P>0.05) among the nine groups. The apparent Se absorption was significantly (P<0.001) higher in T3 supplemented with 150 ppb nano Se. The average daily gain (ADG) was significantly (P<0.05) higher and feed: gain ratio was significantly (P<0.05) lowered in T3 supplemented with 150 ppb nano Se. The results suggested that nano Se supplementation up to 300 ppb had no adverse effect on growth, nutrient intake and digestibility in male Wistar albino rats and nano Se supplementation at 150 ppb exerted a positive effect on growth, protein utilization and apparent selenium absorption in male Wistar albino rats.

REFERENCES

  1. Adkins, R.S and Ewan, R.C. (1984) Effect of supplemental selenium on pancreatic function and nutrient digestibility in the pig. J. Anim. Sci. 58: 351–355.
  2. Albrecht, M. A., Evans, C. W. and Raston, C. L. (2006) Green chemistry and the health implications of nano particles. Green Chem. 8: 417–432.
  3. AOAC (2012) Official Method of Analysis of AOAC International, 19th ed., Association of Analytical Communities International, Virginia, USA.
  4. Beckett, G.J., Beddows, S.E., Morrice, P.C., Nicol, F. and Arthur J.R (1987) Inhibition of hepatic deiodination of thyroxine is caused by selenium deficiency in rats. J. Biochem.248: 433–447.
  5. Bunglavan, S.J., Garg, A.K., Dass, R.S. and Shrivastava, S. (2014) Effect of supplementation of different levels of selenium as nanoparticles/    sodium selenite on blood biochemical profile and humoral immunity in male Wistar rats. Vet. World 7: 1075-1081.
  6. Bunglavan, S.J., Garg, A.K., Dass, R.S., Shrivastava, S. and Chaturvedi, V.K. (2013) Effect of supplementation of different sources of selenium on humoral immunity in guinea pigs. J. Immunol. Immunopathol. 15: 169-174.
  7. Chen, H. J., Yoo, Y., Liu, and Zhao, G. (2011) Green synthesis and characterization of Se nanoparticles and nanorods. Electron. Mater. Lett. 7: 333-336.
  8. Daza, A., Salado, S., Galvez, J.R., Gutierrez-Barquin, M. (2000) Effects of vitamin E and selenium supplementation on the immune system, hematological parameters and the performance of weaned pigs. Investig. Agrar. Prod. Sanid. Anim. 15:21–30.
  9. EEC (2006) Commission Regulation (EC) No 1750/2006 of 27 November 2006 concerning the authorization of selenomethionine as a feed additive.
  10. Ewan, R.C. (1976) Effect of selenium on nitrogen metabolism. J. Nutr. 106: 702–709.
  11. Federal Register (2002) Food additive permitted in feed and drinking water: selenium yeast. Federal Register 67: 46850–46851. 
  12. Hefnawy, A. and Tortora-Perez, J.L. (2010) The importance of selenium and the effects of its deficiency in animal health. Small Ruminant Res. 89: 185–192.
  13. Ingole, A.R., Thakare, S.R., Khati, N.T., Wankhade, A.V. and Burghate, D.K. (2010) Green synthesis of selenium nanoparticles under ambient condition, Chalcogenide Lett. 7: 485 – 489.
  14. Jia, X., Li, N. and Chen, J. A. (2005) A subchronic toxicity study of elemental Nano- Se in Sprague–Dawley rats. Life Sci. J. 76: 1989–    2003. 
  15. Jianhua, H., Ohtsuka, A. and Hayashi K. (2000) Selenium influences growth via thyroid hormone status in broiler chickens. Br. J. Nutr. 84: 727–732.
  16. Kumar, N., Garg, A.K., Mudgal, V., Dass, R.S., Chaturvedi, V.K. and Varshney, V.P. (2008) Effect of different levels of selenium supplementation on growth rate, nutrient utilization, blood metabolic profile, and immune response in lambs. Biol. Trace Elem. Res. 126: S44–S56.
  17. Mahan, D.C. and Parrett, N.A. (1996) Evaluating the efficiency of selenium-enriched yeast and sodium selenite on tissue selenium retention and serum glutathione peroxidase activity in grower and finisher swine. J. Anim. Sci. 74: 2967–2974.
  18. Mahan, D.C. and Peters, J.C. (2004) Long-term effects of dietary organic and inorganic selenium sources and levels on reproducing sows and their progeny. J. Anim. Sci. 82: 1343–1358.
  19. Mahima, C., Garg, A.K., Mittal, G.K. and Mudgal, V. (2010) Effect of organic selenium supplementation on growth, Se uptake, and nutrient utilization in guinea pigs. Biol. Trace Elem. Res. 133: 217–226.
  20. McClure, K.E. and Mahan, D.C. (1988) Effect of dietary selenium source on retention, digestibility and wool accumulation of selenium in growing lambs. Nutr. Rep. Int. 37: 839–846.
  21. Mudgal, V., Garg, A.K. and Dass, R..S. (2007) Effect of dietary selenium and copper supplementation on growth and nutrient utilization in buffalo calves. Anim. Nutr. Feed Techn. 7: 79-88.
  22. Neve, J., (2002) Selenium as a “nutraceutical”: how to conciliate physiological and supra nutritional effects for an essential trace element. Curr. Opin. Clin. Nutr. Metab. Care 5: 659–663.
  23. NRC (1995) Nutrient Requirements of Laboratory Animals, National Research Council, 4th revised edition. The National Academies Press, Washington, DC. p.188.
  24. Payne, R.L. and Southern, L.L. (2005a) Changes in glutathione peroxidase and tissue selenium concentrations of broilers after consuming a diet adequate in selenium. Poultry Sci. 84: 1268–1276.
  25. Payne, R.L. and Southern, L.L. (2005b) Comparison of inorganic and organic selenium sources for broilers. Poultry Sci. 84: 898–902.
  26. Sethy, K., Dass., R.S., Garg., A.K., Sahu., S. and Gogoi, S. (2015) Effect of different selenium sources (Selenium yeast and Sodium selenite) on haematology, blood chemistry and thyroid hormones in male goats (Capra hircus). Indian J. Anim. Res. 49: 788-792. 
  27. Shah, C.P., Singh, K.K., Kumar, M. and Bajaj, P.N. (2010) Vinyl monomers-induced synthesis of polyvinyl alcohol-stabilized selenium nanoparticles. Mater. Res. Bull. 45: 56–62.
  28. Shi, L., Xun, W., Yue, W., Zhang, C., Ren, Y., Shi, L., Wang, Q., Yang, R. and Lei, F. (2011) Effect of sodium selenite, Se-yeast and nano-    elemental selenium on growth performance, Se concentration and antioxidant status in growing male goats. Small Ruminant Res. 96: 49–52.
  29. Snedecor, G.W. and Cochran, W.G. (1989) Statistical Methods, 8th edn. Iowa State University Press, Ames, Iowa 26.
  30. Spallholz, J.E. (1994) On the nature of selenium toxicity and carcinostatic activity. Free Radic. Biol. Med, 17: 45-64.
  31. Steel, R.G.D. and Torrie, J.H. (1980) Principles and Procedures of Statistics. A biometrical approach, 2nd edn. McGraw-Hill International Book Company, New Delhi, India.
  32. Talapatra, S.K., Ray, S.N. and Sen, K.C. (1940) Estimation of phosphorus, chlorine, calcium, magnesium, sodium and potassium in foodstuffs. Indian J. Anim. Sci. 10: 243–246.
  33. Tian, J.Z., Yun, M.S., Kong, C.S., Piao, L.G., Long, H.F., Kim, J.H., Lee, J.H., Lim, J.S., Kim, C.H., Kim, Y.Y. and Han, I.K. (2006) Effects of different products and levels of selenium on growth, nutrient digestibility and selenium retention of growing-finishing pigs. Asian-Austral. J. Anim. 19: 61–66.
  34. Vendeland, S.C, Deagen, J.T., Butler, J.A. and Whanger P.D. (1994) Uptake of selenite, selenomethionine and selenate by brush border membrane vescicle isolated from rat small intestine. Biometals. 7: 305-312.
  35. Zhang, J.S., Gao, X.Y., Zhang, L.D. and Bao, Y.P. (2001) Biological effects of a nano red elemental selenium. Biofactors 15: 27–38.
  36. Zhang, J.S., Wang, H.L., Yan, X.X. and Zhang, L.D. (2005) Comparison of short-term toxicity between Nano-Se and selenite in mice. Life Sci. 76: 1099–1109.
  37. Zhang, J.S., Wang, X.F. and Xu, T.W. (2008) Elemental selenium at nano size (Nano- Se) as a potential chemo preventive agent with reduced risk of selenium toxicity: comparison with Se-methylselenocysteine in mice. Toxicol. Sci. 101: 22–31.
  38. Zhou, X. and Wang, Y. (2011) Influence of dietary nano elemental selenium on growth performance, tissue selenium distribution, meat quality, and glutathione peroxidase activity in Guangxi Yellow chicken. Poult. Sci. 90: 680-686.
  39. Zia, W.M., Khalique, A., Naveed, S. and Hussain, J. (2016) Studies on growth pattern of different body measurements in indigenous Aseel chicken fed with selenium supplemented diets. Indian J. Anim. Res., 51(4): 679-386.
  40. Zia, W.M., Khalique, A., Naveed, S., Hussain, J., Muhammad, N. and Ahmad, S. (2017) Comparative evaluation of influence of dietary organic and inorganic selenium supplement on growth performance of indigenous Aseel chickens Indian J. Anim. Res., 51(3): 478-488 
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