Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

  • NAAS Rating 6.50

  • SJR 0.263

  • Impact Factor 0.4 (2024)

Frequency :
Monthly (January, February, March, April, May, June, July, August, September, October, November and December)
Indexing Services :
Science Citation Index Expanded, BIOSIS Preview, ISI Citation Index, Biological Abstracts, Scopus, AGRICOLA, Google Scholar, CrossRef, CAB Abstracting Journals, Chemical Abstracts, Indian Science Abstracts, EBSCO Indexing Services, Index Copernicus
Submit

Research Article

Indian Journal of Animal Research, volume 51 issue 2 (april 2017) : 336-339

Characterization and anti-fungal susceptibility pattern of dermatophytes isolated from dogs, cats and pet owners in and around Kolkata, India

S. Murmu, C. Debnath, A.K. Pramanik, T. Mitra, S. Jana, S. Banerjee, D.P. Isore, K. Batabyal*
1<p>Faculty of Veterinary and Animal Sciences,&nbsp;West Bengal University of Animal and Fishery Sciences, Kolkata &ndash; 700 037, West Bengal, India.</p>
Cite article:- Murmu S., Debnath C., Pramanik A.K., Mitra T., Jana S., Banerjee S., Isore D.P., Batabyal* K. (2016). Characterization and anti-fungal susceptibility pattern of dermatophytes isolated from dogs, cats and pet owners in and around Kolkata, India . Indian Journal of Animal Research. 51(2): 336-339. doi: 10.18805/ijar.v0i0f.3791.

ABSTRACT

Pet animals mostly suffer from dermatophytic infections and these animals can easily transmit the infection to their handlers or pet owners. Study of 362 clinically suspected cases of dermatophytic infections collected mainly from dogs (n=123), cats (n=202) and few pet owners (n=37) in and around Kolkata, was conducted to detect a total of 285 (78.7%) samples to be positive for significant dermatophytic fungal infections, with cats to be the highest in prevalence (55.4%) followed by dogs (37.9%) and human beings (6.7%) respectively. Microsporum canis (60.0%) was the most prevalent pathogen in comparison to M. gypseum (22.5%), Trychophyton mentagrophytes (15.8%) and T. rubrum (1.7%) affecting dogs, cats and human beings. T. rubrum was detected only from human cases in this study. Male dogs (58.3%), cats (51.3%) and human patients (78.9%) were mostly infected than the female ones. The anti-fungal susceptibility pattern of these isolates revealed lower MIC50 values of 0.06-0.125µg/ml for Ketoconazole, Itraconazole, Miconazole, and Amphotericin-B but not for Fluconazole (8-16µg/ml). The MIC90 values of these antifungal agents were as low as 0.03µg/ml for all drugs except Fluconazole (32µg/ml). 

REFERENCES


  1. Alpun, G. and Ozgur, N.Y. (2009). Mycological Examination of Microsporum canis Infection in Suspected Dermatophytosis of Owned and Ownerless Cats and Its Asymptomatic Carriage. J. Anim. Vet. Adv., 5: 803-806.

  2. Brilhante, R.S.N., Cavalcante, C.S.P., Soares-Junior, F.A., Cordeiro, R.A., Sidrim, J.J.C. and Rocha, M.F.G. (2003). High rate of Microsporum canis, feline and canine dermatophytoses in North-East Brazil: Epidemiological and diagnostic features. Mycopathol., 156: 303-308.

  3. Day, M.J., Breitschwerdt, E., Cleaveland, S., Karkare, U., Khanna, C., Kirpensteijn, J., Kuiken, T., Lappin, M.R., McQuiston, J., Mumford, E., Myers, T., Palatnik-de-Sousa, C.B., Rubin, C., Takashima, G. and Thiermann, A. (2012). Surveillance of Zoonotic Infectious Disease transmitted by Small Companion Animals. Emerg. Infect. Dis., 18: Online Report.

  4. Esch, K.J. and Petersen, C.A. (2013). Transmission and epidemiology of zoonotic protozoal diseases of companion animals. Clin. Microbiol. Rev., 26: 58-85. 

  5. Espinel-Ingroff, A. (2001). In-vitro fungicidal activities of voriconazole, itraconazole and amphotericin B against opportunistic moniliaceous and dermatiaceous fungi. J. Clin. Microbiol., 39: 954-958. 

  6. Falahati, M., Akhlaghi, L., Lari, A.R. and Alaghehbandan, R. (2003). Epidemiology of dermatophytosis in an area south of Tehran, Iran. Mycopathol., 156: 279-287.

  7. Gangil, R., Dutta, P., Tripathi, R., Singathia, R. and Lakhotia, R.L. (2012). Incidence of dermatophytosis in canine cases presented at Apollo Veterinary College, Rajashtan, India. Vet. World, 5: 682-684.

  8. Jessup, C.J., Ryder, N.S. and Ghannoum, M.A. (2000). An evaluation of the in-vitro activity of terbinafine. Med. Mycol., 38: 155-159.

  9. Koneman, E.W. and Roberts, G.D. (1985). Dermatophyte identification schema. In: Practical Laboratory Mycology, 3rd edn, Williams & Wilkins, Baltimore, MD.

  10. Mattei, A.S., Beber, M.A. and Madrid, I.M. (2014). Dermatophytosis in Small Animals. SOJ Microbiol. Infect. Dis., 2: 1-6.

  11. Moretti, A., Agnetti, F., Mancianti, F., Nardoni, S., Righi, C., Moretta, I., Morganti, G. and Papini, M. (2013). Dermatophytosis in animals: epidemiological, clinical and zoonotic aspects. Giornale Italiano di permatologia e Venereologia, 148: 563-572.

  12. Ngwogu, A.C. and Otokunefor, T.V. (2007). Epidemiology of dermatophytoses in a rural community in Eastern Nigeria and review of literature from Africa. Mycopathol., 164: 149-158. 

  13. Nilce, M., Martinez-Rossi, A.E., Nulu, T.A., Peres, A.E. and Rossi, A. (2008). Antifungal Resistance Mechanism in Dermatophytes. Mycopathol., 166: 369-383. 

  14. Nweze, E.I. (2011). Dermatophytoses in domesticated animals. Revista do Instituto de Medicina Tropical de São Paulo, 53: 95-99.

  15. Robert, R. and Pihet, M. (2008). Conventional Methods for the Diagnosis of Dermatophytosis. Mycopathol., 166: 295-    306. 

  16. Ruben, L.M. (2010). Candidosis, a new challenge. Clin. Dermatol., 28: 178-184.

  17. Santos, D.A., Barros, M.E.S. and Hamdan, J.S. (2006). Establishing a method of inoculum preparation for susceptibility testing of Trichophyton rubrum and Trichophyton mentagrophytes. J. Clin. Microbiol., 44: 98-101. 

  18. Seker E. and Dogan, N. (2011). Isolation of dermatophytes from dogs and cats with suspected dermatophytosis in Western Turkey. Preventive Vety. Medicine. 98: 46-51.

  19. Sharma, D.K., Joshi, G., Singathia, R. and Lakhotia, R.L. (2009). Zooanthroponosis of Microsporum gypseum infection. Haryana Vet., 48: 108-109.

  20. Snedecor, G.W. and Cochran, W.G. (1994). Statistical Methods. 1st edn., East-West Press. New Delhi.

  21. Sparkes, A.H., Gruffydd-Jones, T.J., Shaw, S.E., Wright, A.I. and Stokes, C.R. (1993). Epidemilogical and diagnostic features of canine and feline dermatophytosis in the United Kingdom from 1956 to 1991. Vet. Rec., 17: 57-61.

  22. Stojanov, I.M., Prodanov, J.Z., Pusic, I.M. and Ratajac, R.D. (2009). Dermatomycosis - A Potential Source of Zoonotic infection in Cities. Proc. Natur. Scs. published by Matica Srpska, Novi. Sad Sebia, 116: 275-280.

  23. Venkatesan, G., Ranjit Singh, A.J.A., Muregesan, A.G., Janaki, C. and Gokul Shankar, S. (2007). Trichophyton rubrum – the predominant etiological agent in human dermatophytoses in Chennai, India. African J. Microbiol. Res., 1: 09-012.

     
Reviewed By

Download Article
In this Article
    Contact us
    Follow us

    Editorial Board

    View all (0)