Indian Journal of Animal Research

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Research Article

Indian Journal of Animal Research, volume 51 issue 1 (february 2017) : 97-104

Evaluation of aspirin (ASA) in broiler chicken during hot dry summer using zoo technical, molecular and physio-biochemical tools

J.J. Rokade*, S.K. Bhanja, A.S. Shinde, Sajjad, Darshana B. Bhaisare, A.B. Mandal
1<p>Central Avian Research Institute,&nbsp;Izatnagar-243 122, UP, India.</p>
Cite article:- Rokade* J.J., Bhanja S.K., Shinde A.S., Sajjad, Bhaisare B. Darshana, Mandal A.B. (2016). Evaluation of aspirin (ASA) in broiler chicken during hot dry summer using zoo technical, molecular and physio-biochemical tools . Indian Journal of Animal Research. 51(1): 97-104. doi: 10.18805/ijar.v0iOF.6836.

ABSTRACT

The present study was undertaken to evaluate the efficacy of aspirin as anti-heat stressor. Broiler chicks were reared on a standard diet up to 14 days of age. Thereafter, the chicks were randomly distributed into three dietary treatment groups viz., T1 (Control group: Standard diet), T2 (Standard diet with aspirin@250 mg/kg) and T3 (Standard diet with aspirin@500 mg/kg). Each treatment was having five replicates of eight birds per replicate. Experiment was carried out during hot-dry (April-May, 30.0±0.70 to 37.0±1.40C, Rh, %: 58.05±1.32 to 70.11±0.82) summer. Feed intake and live weight gain was comparable among the treatments but FCR, protein and energy efficiency improved significantly (P<0.001) on aspirin supplementation. The relative yield of thymus and bursa at 4th and 6th week of age improved significantly (P<0.05). The percentage of protein, aspartate transaminase (AST) and alanine transaminase (ALT) increased significantly (P<0.001) due to aspirin supplementation at 4th as well as 6th week of age. While H:L ratio, serum corticosteron and serum cholesterol (only at 42nd day of age) decreased significantly (P<0.001) in aspirin supplemented groups at 28th as well as 42nd day of age. Supplementation of aspirin at 500 mg/kg reduced relative expression of HSP70 in jejunum tissues during 28th or 42nd day of age. It can be concluded that aspirin supplementation 500 mg/kg in diet of heat stressed broilers improved performance as well as welfare.

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