Activity of different serum enzymes and hormone profile in foot and mouth disease affected cattle

DOI: 10.18805/ijar.v0i0f.3810    | Article Id: B-2808 | Page : 826-827
Citation :- Activity of different serum enzymes and hormone profilein foot and mouth disease affected cattle .Indian Journal Of Animal Research.2016.(50):826-827

J. Barkakati, S. Sarma, D.J. Kalita*, J. Goswami and K. Sharma
Address :

Department of Veterinary Biochemistry, College of Veterinary Science, Assam Agricultural University, Guwahati, Khanapara-781 022, India.


Present study was undertaken to elucidate the effect of Foot and Mouth Disease on the activity of different serum enzymes and hormone profile in indigenous cattle of Assam. The serum alkaline phosphatase (ALP) and alanine transaminase (ALT) activity did not show significant difference among the affected, recovered and control group. However, significant (P<0.01) increase of aspartate transaminase (AST) activity was recorded in the affected group as compared to control. The level of T3 showed a significant (P<0.05) increase during FMD infection. T4 and cortisol hormones were also found to be increased significantly (P<0.01) in FMD affected than recovered and control group. From the present study, it can be concluded that during FMD, there is a significant increase of AST , T3, T4  and  cortisol. However, no significant change was recorded in the activity of ALT and ALP during FMD infection and recovered group.


Cattle Foot- and -Mouth Disease Hormone Serum enzyme.


  1. Adcock, R. J., Kattesh,H.G., Roberts, M .P., Carroll, J. A., Saxtonand , A. M. and Kojima, C. J. (2007) .Temporal relationship between plasma cortisol. Corticosteroid –binding –globulin (CBG) and the free cortisol index (FCI) in pigs in response to adrenal stimulation or suppression. Int. J. on the Biol. of Stress.10: 305-310.
  2. Alexandersen, S., Zhang, Z. and Donaldson, A. I. (2002). Aspects of the persistence of foot-and-mouth disease virus in animals—the carrier problem. Microbes Infection. 4: 1099-110. 
  3. Chase, C. C., Larsen, R. E., Randel, R. D., Hammond, A. C. and Adams, E. L .(1995). Plasma cortisol and white blood cell response of bulls: A comparison of two methods of castration. J.Anim Sci. 73: 975-980.
  4. Gattani, A., Gupta, K .K., Joshi, G. and Gupta, S.R. (2011). Metabolic profile of foot and mouth disease stressed sheep in Gokce, G., Gokce,V., Gunes, H. M. and Citil, M.(2004). Alterations in some haematological biochemical parameters in cattle suffering from FMD .Turk J. Anim. Sci. 28: 723-727.
  5. Gruys, E. M., Toussaint, T., Niewold, S. and Koopmans, S. (2005).Acute phase reaction and acute phase proteins. J. Zhejiang Univ. Sci. 6: 1045-1056.
  6. Kaneko, J.J., Harvey, J.W. and Bruss, M.L. (1997). Clinical Biochemistry of Domestic Animals. Fifth edn. Academic press, New York, Pp. 661- 668. 
  7. Kitching, R.P.(2002). Identification of foot and mouth disease virus carrier and subclinically infected animals and differentiation from vaccinated animals. Rev. Sci. Tech. Off. Int. Epiz. 21: 531–538.
  8. Lal, L. G. S. (1981). Relation between serum protein bound iodine (PBI) with disease stress (FMD in Tharparkar cows. Indian Vet. J. 58: 646-648.
  9. Nahed, S. T. (2010). Investigation of Serum Insulin and Cortisol Concentrations in Foot and Mouth Disease infected cattle in Relation to changes in Serum Biochemical Variables and Protein Electrophoretic Fractionation Profile. Glob. Veterinar. 4: 450-455. 
  10. Roman, G. R. (1995).Comparative studies concerning the effects of hydrocortisone and of some synthetic glucocorticoids upon the thymocytes of the Wistar rats. Roman J. Physiol. 32: 83-86.

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