INFLUENCE OF AMBIENT TEMPERATURE AND HUMIDITY ON ATP1A1 GENE EXPRESSION IN THARPARKAR AND VRINDAVANI CATTLE
Citation :- INFLUENCE OF AMBIENT TEMPERATURE AND HUMIDITY ON ATP1A1 GENE EXPRESSION IN THARPARKAR AND VRINDAVANI CATTLE.Indian Journal Of Animal Research.2014.(48):541-544
The Na+/K+-ATPase is responsible for maintenance of the Na+ and K+gradients across the plasma membrane and responds to alteration in oxidative voltage and osmotic changes across membranes. ATP1A1 gene encodes for the a-1 chain of the Na+/K+-ATPase and there exists a positive linear correlation between Na+/K+-ATPase activity and mRNA level of a-1 isoforms. Present study aimed at exploring influence of temperature-humidity variation in winter, spring and summer test-periods on the expression of ATP1A1between Tharparkar and Vrindavani (cross of Holstein Frisian, Jersey and Brown Swiss withHariana) cattle. The value for THI were highest for summer (84.34), followed by spring (68.25) and lowest for winter (52.72),thus spring was consideredas reference season.Vrindavaniand Tharparkar both showed up-regulation of ATP1A1 expression in summer as well as inwinter.Higherup-regulationwas observed in summer. The up-regulation in Vrindavani was significantly higher than Tharparkar in both winter and summer seasons.
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