Indian Journal of Animal Research

  • Chief EditorM. R. Saseendranath

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Indian Journal of Animal Research, volume 49 issue 4 (august 2015) : 498-502

Detection of exogenous Jaagsiekte sheep retrovirus in Turkey

Kezban Can-Sahna, Yesari Eroksuz, Engin Berber, Ibrahim Sozdutmaz
1Faculty of Veterinary Medicine, University of Firat, Elazig, Turkey.
Cite article:- Can-Sahna Kezban, Eroksuz Yesari, Berber Engin, Sozdutmaz Ibrahim (2025). Detection of exogenous Jaagsiekte sheep retrovirus in Turkey. Indian Journal of Animal Research. 49(4): 498-502. doi: 10.5958/0976-0555.2015.00053.9.

ABSTRACT

The aim of this study is to detect the exogenous Jaagsiekte sheep retrovirus (exJSRV) in suspected cases of ovine pulmonary adenocarcinoma (OPA) from the Eastern Anatolian region of Turkey. Pathological examination and PCR were carried out with the lung, lymph nodule, brain, heart and liver tissues of four sheep with suspected OPA. Histology of the lung sections indicated the well-circumscribed, multifocal and unencapsulated gray to white masses (arrows) on the parietal surface of medial and caudal lobes. exJSRV was detected in all tissue samples except for brain by nested polymerase chain reaction (nPCR). In addition to the nested-PCR results, the presence of exJSRV into the clinical samples was confirmed with sequencing of two PCR-positive products for OPAV. This report highlights the first presence of exJSRV in the sheep suspected with OPA in Turkey. Furthermore, the results provide supporting evidence for the metastasis of exJSRV in extra-thoracic tissues.

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