Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

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Indian Journal of Animal Research, volume 49 issue 5 (october 2015) : 704-708

Effectiveness of levamisole and tarantula cubensis extract in the treatment of teat Papillomatosis of cows

Zahid Paksoy, Nuri Gülesci, Fatih Mehmet Kandemir, Güngör Çagdas Dinçel
1Gümüshane University, Gümüshane Vocational School, Veterinary Sciences, 29000, Gümüshane, Turkey.
Cite article:- Paksoy Zahid, Gülesci Nuri, Kandemir Mehmet Fatih, Dinçel Çagdas Güngör (2024). Effectiveness of levamisole and tarantula cubensis extract in the treatment of teat Papillomatosis of cows. Indian Journal of Animal Research. 49(5): 704-708. doi: 10.18805/ijar.5586.
Papillomatosis is widespread in cattle and is often observed on the skin of udders. For treatment, anthelmintic, immunomodulator and homeopathic drugs are administered. The objective of the study was to examine the therapeutic effect of levamisole and tarantula cubensis extract in the treatment of papilloma observed in the teats of cows. Sixteen Holstein cows between the age of 2-3 years were used as study material. The cows with Papillomatosis were randomly assigned into two equal groups. The animals in the first group (n=8) were treated with intramuscular double doses of levamisole (5 mg/kg) applied one week apart. The second group of animals (n=8) was treated with two subcutaneous doses of 10 ml of Tarantula cubensis extract one week apart. Four animals in the first group recovered while 8 animals in the second group recovered. The total serum oxidant levels of the animals treated with Tarantula cubensis extract and levamisole on the 15th day was found to be significantly lower than the serum levels of same animals on day 0 of the treatment (P
  1. Anonymous (2013). Interhas A.S. Veteriner Ilaçlari website. Theranekron, Available at: http://www.interhas.com/tr/ urun.asp?sayfa=Theranekron. Accessed January 15, 2013.
  2. Apaydin, A.M., Aydin, M., Ciftci, O., Timurkaan, N., Yildiz, H. and Tonbak S. (2010). Effects of Paronychia kurdica on teat and udder papillomatosis in cows. Rev Med Vet 161: 267-271.
  3. Aslan, Ö. and Saraç, S. (2011). Sigir Papillomatozisinde lipid peroksidasyon düzeyi ve Antioksidan enzim aktiviteleri. J Fac Vet Med Univ Erciyes 8: 75-81.
  4. Baydan E, (1995). Immünodepresant ve Imunostimulantlar. Ankara Univ Vet Fak Derg, 42: 45-56.
  5. Biricik, H.S., Keskin, O., Çimtay, I. and Baba, ZF. (2003). Sigir papillomatozisinin tedavisinde otolog asi ve otohemoterapi uygulamalarinin karsilastirilmasi. Turk J Vet Anim Sci 27: 703-707.
  6. Börkü, M.K., Atalay, O., Kibar, M., Cam, Y. and Atasever, A. (2007). Ivermectin is an effective treatment for bovine cutaneous papillomatosis. Res Vet Sci 83: 360-363.
  7. Cam, Y., Kibar, M., Atasever, A., Atalay, O. and Beyaz, L. (2007). Efficacy of levamisole and Tarantula cubensis venom for the treatment of bovine cutaneous papillomatosis. Vet Rec 160: 486-488.
  8. Çimtay, I., Biricik, H.S., Keskin, O. and Baba, ZF. (2003). Sigir papillomatozisinin sagaltiminda farkli asilama yöntemlerinin etkinligi üzerine karsilastirmali arastirmalar. Turk J Vet Anim Sci 27: 929-933.
  9. Erel, O. (2004). A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem 37: 277–285.
  10. Erel, O. (2005). A new automated colorimetric method for measuring total oxidant status. Clin Biochem 38: 1103–1111.
  11. Gültiken, N. and Vural, MR. (2007). The Effect of Tarantula Cubensis Extract Applied in Pre and Postoperative Period of Canine Mammary Tumours. JIVS 2: 13-23. [ JIVS (Journal of Istanbul Veterinary Sciences)]
  12. Hemmatzadeh, F., Fatemi, A. and Amini, F. (2003). Therapeutic effects of fig tree latex on bovine papillomatosis. J Vet Med B Infect Dis Vet Public Health 50: 473-476.
  13. Icen, H., Sekin, S., Simsek, A., Kochan, A. and Tunik, S. (2011). The Efficacy of Tarantula cubensis Extract (Theranekron) in Treatment of Canine Oral Papillomatosis. Asian J Anim Vet Adv 6: 744-749.
  14. Kirmizigül, A.H., Gökçe, E., Sözmen, M., Yildirim, Y. and Beytut, E. (2010). Ivermektin’in sigir deri papillomatozisinde tedavi etkinligi. Kafkas Univ Vet Fak Derg 16: 627-631.
  15. Lanusse, C.E., Alvarez, L.I., Sallovitz, J.M., Mottier, M.L., and Bruni, S.F.S. (2009). Antinematodal Drugs. In: Veterinary pharmacology and therapeutics. 9th ed. (JE Riviere, MG Papich eds). Iowa: Wiley-Blackwell Publishing, pp: 1076-1079.
  16. Maclachlan, N.J., and Dubovi, E.J. (2011). Fenner’s Veterinary Virology. 4th ed. London, Academic Press, pp: 218-219.
  17. Öcal, H., Yildiz, A., Apaydin, A.M., and Kaygusuzoglu, E. (2001). Inek ve Düvelerde Meme Papillomatozisinin Tedavisi ve Etiyolojisi Üzerine Çalisma. Firat Univ Saglik Bilim Derg 15: 23-26.
  18. Özyurtlu, N., and Aslan, S. (2007). Homeopati ve Veteriner Hekimliginde Kullanimi. Veteriner Hekimler Dernegi Dergisi 78: 39-42.
  19. Wellenberg, G.J., Van der Poel, W.H., and Van Oirschot, J.T. (2002). Viral infections and bovine mastitis: a review. Vet Microbiol 2: 27-45.

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