EFFECT OF INJECTABLE SODIUM SELENITE ON THE LEVEL OF STRESS BIOMARKERS IN MALE AARDI GOATS

DOI: 10.5958/j.0976-0555.48.3.051    | Article Id: B-153 | Page : 239-243
Citation :- EFFECT OF INJECTABLE SODIUM SELENITE ON THE LEVEL OF STRESS BIOMARKERS IN MALE AARDI GOATS.Indian Journal Of Animal Research.2014.(48):239-243
A. Haj Elsheikh, M.J. Al-Hassan, H.E. Mohamed* and A.M. Abudabos hmohamedd@ksu.edu.sa
Address : Department of Animal Production, College of Food and Agriculture Sciences, King Saud University, Saudi Arabia

Abstract

The aim of the present study was to evaluate the effects of sodium selenite (SS) injection on plasma concentrations of selenium (Se), glutathione peroxidase (GSH-Px); Malondialdehyde (MDA), and cortisol. A total of twenty seven male Aardi goats were randomly divided into three equal groups ; group I (control, fed selenium deficient diet),  II (injected with 0.01 mg SS/kg body weight) and III (injected with 0.05 mg SS /kg body weight). Plasma selenium levels differed significantly between treatment and control groups from week one to week three. Level of GSH-Px also differed significantly between the groups. Cortisol varied according to selenium supplementation in week one, two and three. Sodium selenite injection significantly increased Se levels in plasma of Aardi goats as compared with the control group. In conclusion, sodium selenite treatment to Aardi goats minimized the stress level in male Aardi goats, and it was difficult from the experimental design to recommend one of the two doses as therapeutic or preventive anti stress protocols.

Keywords

Aardi goats Cortisol Lipid peroxdation Selenium.

References

  1. Akil M, Gurbuz U, Bicer M, Sivrikaya A, Mogulkoc R, Baltaci AK, (2011). Effect of selenium supplementation on lipid peroxidation, antioxidant enzymes, and lactate levels in rats immediately after acute swimming exercise. Biological Research 142: 651-659.
  2. Alamer M, (2009). Effect of water restriction on lactation performance of Aardi goats under heat stress conditions. Small Ruminant Research 84: 76-81.
  3. Al-Saleh IA, Al-Jaloud A, Al-Doush I, and El-Din G (1999) .The distribution of selenium levels in Saudi dairy farms: a preliminary report from Al-Kharj. Journal Environmental Pathology Toxicology 8:37-46.
  4. Athamna OM, Bengoumi M, Faye, B, (2012). Selenium and copper status of camels in Al-Jouf area (Saudi Arabia). Tropical Animal Health and Production 44: 551-556
  5. Behne D, Kyriakopoulos A, (2001). Mammalian selenium containing proteins. Annals Review Nutrition 21: 453
  6. Chadio SE, Kotsampasi BM, Menegatos JG, Zervas GP, Kalogiannis DG, (2006). Effect of selenium supplementation on thyroid hormone levels and selenoenzyme activities in growing lambs. Biology Trace Element Research 109:145-54.
  7. Combs GF Jr, and Combs SB, (1986). The Role of Selenium in Nutrition, Academic Press, Inc., 532 p.
  8. Chung JY, Kim JH, Ko YH, Jang IS, (2007). Effects of Dietary Supplemented Inorganic and Organic Selenium on Antioxidant Defense Systems in the Intestine, Serum, Liver and Muscle of Korean Native Goats. Asian-Australian Journal Animal Science 20: 52 – 59
  9. Dercksen DP, Counotte GH, Hazebroek MK, Arts W, van Rijn T, (2007). Selenium requirements of dairy goats. Tijdschr Diergeneeskd. 132:468-71. “Article in Dutch”
  10. El-Neweehy, TK, Abdel-Rahman, HA, Al-Qarawi, AA, (2001). Some studies on nutritional muscular dystrophy in Qassim region in Saudi Arabia. Effect of administration of Vitamin E-selenium preparation to pregnant ewes on serum muscle-specific enzymes in their lambs. Small Ruminant Research 41:87-89.
  11. Gunes V, Ozcan K, Citil M, Onmaz AC, Erdogan, HM, (2010). Detection of myocardial degeneration with point-of-care cardiac troponin assays and histopathology in lambs with white muscle disease. The Veterinary Journal 184: 376-14378.
  12. Gupta, U.C., Gupta, S.C, (2000). Selenium in soils and crops, its deficiencies in livestock and humans: Implications for management. Communications In Soil Science and Plant Aanalysis, 31: 1791-1807
  13. Gutzwiller A, (1991). The effect of the selenium status of goats on the resistance of erythrocytes to oxidative damage. Schweizer Archiv fur Tierheilkunde 133: 157-161.
  14. Islam F, Zia S, Sayeed I, Zafar KS, Ahmad AS, (2002). Selenium-induced alteration of lipids, lipid peroxidation, and thiol group in circadian rhythm centers of rat. Biology Trace Element Research 90:203-14.
  15. Jimenez, A., Andres, S., Sanchez, J., Barrera, R., Benito, M., Mane, M.C., (1998). Evaluation of different prophylactic methods against selenium deficiency in sheep grazing on range in southwestern spain. Small Rumin. Res., 29:193-199.
  16. Kumar, N., Garg, A.K., Dass, R.S., Chaturvedi, V.K., Mudgal, V., Varshney, V.P., (2009). Selenium supplementation influences growth performance, antioxidant status and immune response in lambs. Animal Feed Science and Technology 153: 77– 87.
  17. Miller, LL, Hontela A, (2011). Species-specific sensitivity to selenium-induced impairment of cortisol secretion in adrenocortical cells of rainbow trout (Oncorhynchus mykiss) and brook trout (Salvelinus fontinalis). Toxicology Applied Pharmacology 253:137-44.
  18. Misurova, L., Pavlata, L., Pechova, A., Dvorak, R., (2009). Effect of a long-term peroral supplementation with sodium selenite and selenium lactate-protein complex on selenium status in goats and their kids. Veterinari Medicina 54: 324-332
  19. Möstl E, Palme R, (2002). Hormones as indicators of stress. Domestic Animal Endocrinology 23: 67–74.
  20. Nielsen F, Mikkelsen BB, Nielsen JB, Andersen HR, Grandjean, P, (1997). Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clinical Chemistry 43:1209-1214.
  21. NRC, (2005). Selenium. In: Mineral Tolerance of Domestic Animals.:National Academy Press. Washington, D.C. pp321–347 Paglia DE, Valentine WN, (1967). Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. Journal of Laboratory Clinical Medicine 70: 158–169.
  22. Ramirez-Bribiesca JE, Tortora JL, Huerta M, Hernandez, LM, Lopez R, Cosby MM, (2005). Effect of selenium-vitamin E injection in selenium-deficient dairy goats and kids on the Mexican plateau. Arquivo Brasileiro De Medicina Veterinaria Ezootecnia 57: 77-84.
  23. Saini RK, Saini N, Kataria M, Babu, S, (2007). Effect of selenium and alpha-tocopherol on the antioxidant defense system of goat erythrocytes and the hemic system. Toxicology Mechanisms and Methods 17: 117-123.
  24. Sanchez. J., Montes. P., Jimenez. A., Andres, S., (2007). Prevention of clinical mastitis with barium selenate in dairy goats from a selenium-deficient area. Journal of Dairy Science 90: 2350-2354.
  25. Sevcikova L, Pechova, A, Pavlata, L, Antos, D, Mala, E, Palenik, T, Panev, A, Dvorak, R, (2011). The Effect of Various Forms of Selenium Supplied to Pregnant Goats on the Levels of Selenium in the Body of Their Kids at the Time of Weaning. Biological Trace Elements Research 143: 882-892
  26. Shi L, Xun W, Yue W, Zhang C, Ren Y, Shi, L, Wang Q, Yang R, Lei F, (2011). Effect of sodium selenite, Se-yeast and nano-elemental selenium on growth performance, Se concentration and antioxidant status in growing male goats. Small Ruminants Research 96: 49-52
  27. Stowe HD, Herdt TH, (1992). Clinical assessment of selenium status of livestock. Journal Animal Science 70: 3928- 3933.
  28. Tiran B, Tiran A, Petek W, Rossipal E, Wawschinek, O, (1992). Selenium status of healthy children and adults in styria (Austria). Trace Elements Medicine, (2): 1975–79.
  29. Wang YX, Zhan WA, Yuan D, Zhang, XW Wu RJ, (2011). Effects of selenomethionine and sodium selenite supplementation on meat quality, selenium distribution and antioxidant status in broilers. Czech Journal Animal Science 56: 305–27313.
  30. Yue WB, Zhang CX, Shi LG, Ren YS, Jiang YS, Kleemann, DO, (2009). Effect of Supplemental Selenomethionine on Growth Performance and Serum Antioxidant Status in Taihang Black Goats. Asian-Australian Journal of Animal Sciences 22: 365-370

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