Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

  • NAAS Rating 6.50

  • SJR 0.263

  • Impact Factor 0.5 (2023)

Frequency :
Monthly (January, February, March, April, May, June, July, August, September, October, November and December)
Indexing Services :
Science Citation Index Expanded, BIOSIS Preview, ISI Citation Index, Biological Abstracts, Scopus, AGRICOLA, Google Scholar, CrossRef, CAB Abstracting Journals, Chemical Abstracts, Indian Science Abstracts, EBSCO Indexing Services, Index Copernicus
Indian Journal of Animal Research, volume 54 issue 2 (february 2020) : 138-142

Analysis on correlation between polymorphism of MyoG gene exon I and body size traits of sheep

Jun. Yan. Bai, Heng.Cao, You. Bing .Yang, Yi .Zhang, Xin.Yue.Li, Zi.Heng.Li, Wei.Guang.Hao, Fei.Yang.Zheng
1<div style="text-align:justify">College of Animal Science and Technology,</div><div>Henan University of Science and Technology, Luoyang 471 003, China.</div>
Cite article:- Bai Yan. Jun., Heng.Cao, .Yang Bing You., .Zhang Yi, Xin.Yue.Li, Zi.Heng.Li, Wei.Guang.Hao, Fei.Yang.Zheng (2019). Analysis on correlation between polymorphism of MyoG gene exon I and body size traits of sheep. Indian Journal of Animal Research. 54(2): 138-142. doi: 10.18805/ijar.B-1081.
Myogenin (MyoG) is responsible for centering control over myocyte differentiation process and can influence the meat production of animals directly. Large tailed Han sheep, small tailed Han sheep, Yuxi fatty tailed sheep, Lanzhou large tailed sheep, Mongolia sheep and Tong Sheep were used as the experimental materials in this study. Polymorphism of MyoG gene exon I was tested by native polyacrylamide gel electrophoresis. The correlation between polymorphism of MyoG gene exon I and body size traits was analyzed. Influences of MyoG gene exon I on growth traits of sheep were discussed. Results demonstrated that 2 alleles (A, B) and 3 genotypes (AA, BB and AB) were detected in MyoG gene exon I of all 6 sheep varieties. The A allele frequencies in MyoG gene exon I of small tailed Han sheep, large tailed Han sheep, Yuxi fatty tailed sheep, Lanzhou large tailed sheep, Mongolia sheep and Tong Sheep were 0.5167, 0.2500, 0.4376, 0.6500, 0.5750 and 0.7125, while the B allele frequencies were 0.4833, 0.7500, 0.5625, 0.3500, 0.4250 and 0.2875, respectively. Chest width and neck length of the AA genotype of MyoG gene exon I were significantly higher than those of the AB genotype (P<0.01) and BB genotype (P<0.05). Body length and rump length of the AA genotype were significantly higher than those of the AB genotype (P<0.05). The chest depth and hip width of the AA genotype was far lower than that of the AB genotype (P<0.01). The hip height of the AA genotype was far lower than that of the BB genotype (P<0.05).
  1. Abdelmoneim, T. S., Brooks, P.H., Afifi, M., and Swelum,A.A.A. (2017). Sequencing of growth hormone gene for detection of polymorphisms and their relationship with body weight in Harri sheep. Indian Journal of Animal, 51 (2): 205-211. DOI:10. 18805 /ijar.11457.
  2. Anton,I.,Zsolnai, A.,Komlósi, I.,Király,A. and .Fésüs,L. (2006). Effect of MYOG genotypes on growth rate and production traits in Hungarian large white pigs. Acta Veterinaria Hungarica., 54(3): 393-397. https://doi.org/10.1556/ AVet.54.2006.3.9.
  3. Bai,J.Y.,Jia,X.P.,Yang,Y.B.,Pang,Y.Z and Wang,Y.Q. (2017a). Study on the polymorphism of fibroblast growth facor receptor (FGFR1) in sheep. Indian Journal of Animal Research, 51 (5):856-859. DOI:10.18805/ijar.v0iOF.4551.
  4. Bai,J.Y.,Wang,X.,Yang,Y.B.,Zhang,X.H.,Pang,Y.Z.,Li,H.W. (2016). Study on the polymorphism of POU1F1 gene in sheep. Revista Brasileira de Zootecnia, 45(10): 604-607. http://dx.doi.org/ 10.1590/S1806-92902016001000004.
  5. Bai,J.Y., Yang,Y.B., Wang,Y.Q., Pang,Y.Z., Wang,X., Yang, S. and Yang, H.L. (2017b). Polymorphism of MyoG Gene Exon 1 and its association analysis with meat quality traits in sheep. China Animal Husbandry & Veterinary Medicine, 6:1778-1783.
  6. Bai,J.Y.,Yang,Y.B.,Wang,Y.Q.,Zhang,X.H. and Pang,Y.Z. (2015). Polymorphism analysis of three Chinese indigenous sheep breeds by microsatellite markers. Indian Journal of Animal Research, 49 (5): 585-590. DOI: 10.18805/ijar.5566. 
  7. Bhutan,M.S.A.,Kim,N.K.,Cho,Y.M.,Yoon,D.,Kim,K.S.,Jeon,J.T.and Lee,J.H. (2009). Identification of SNPs in MYOD gene family and their associations with carcass traits in cattle. Livestock .Science., 126(1):292-297. DOI: 10.1016/j.livsci.2009.05.019.
  8. Chai,Z.X., Xin,J.W., Wang,H., Guo,L., Zhong,J.H., Zhang,C.F., Ji,Q.M. (2018). Polymorphisms of MyoG Gene and Analysis of Relevance with Growth Performances in Yak. Acta Agriculturae Boreali-Sinica, 33(6):108-115.
  9. Chu,M.X.,He,Q.Y.,Wang,J.Y.,Olajide,O.,Ye,S.C. and Fang, L.(2005). PCR-SSCP Analysis on Exon 1 of Myogenin Gene in sheep. Journal of Agricultural Biotechnology., 13(1): 77-80.
  10. Gao,G.Y.,Wang,J.,Wang,Y.,Fu,C.X.,Zhou,G.M., Zhou,L.X. and Wang,C.X. (2009). Cloning and sequence analysis of MyoGenin of Chengdu Grey Goats. Journal of Southwest University for Nationalities (Natrual Science Edition)., 35(1):84-88.
  11. Gao,Q.X.,Liu,M.,Yang,Y.Q.and Wang,L.Y.(2005). Polymorphism analysis of porcine MyoG Gene by PCR-RFLP and its association with growth traits and fiber number. Chinese Journal of Veterinary Science., 25(3).330-332.
  12. Han,Y.C.,Sun,Y.G.,Chen,Z.(2016). Single Nnucleotide Polymorphism of MyoG Gene in Tibetan Sheep Populations and its Association with Body Measurement Traits. Acta Ecologae Animalis Domastici. 37(6):19-23
  13. Hasty,P.Bradley,A.Morris,J.H.Edmondson,D.G.Venuti,J.M.Olson,E.N. and Klein,W.H. (1993). Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. Nature., 364(6437):501-506. http://dx.doi.org/10.1590/S1806- 92902016001000004.
  14. Kim,J.M.,Choi,B.D.,Kim,B.C.,Park,S.S. and Hong,K.C.(2009). Associations of the variation in the porcine cryogenic gene with muscle fibre characteristics,lean meat production and meat quality traits.Animal Breeding Genetie .,126(2):134-141.
  15. Liu,Y.B.,Wang,F.,Deng,F.,Tian,C.Y.,Liu,M.X.,Liang,Z.J. and Rong,W.H. (2007). Analysis on single nucleotide polymorphisms of Exon of MyoG Gene in different sheep breeds. Acta Veterinaria et Zootechnica Sinica., 38(12)1294-1299.
  16. Liu,Z.Z.,Zhang,W.X.,Zhang,C.S.,Gong,Y.F.and Liu,X.R. (2009). Polymorphism analysis of the MyoG Gene digested with Csp6I in goat. Acta Agriculturae Universitatis Jiangxinesis (Natrual Science Edition)., 31(2):317-321.
  17. Liu,Z.Z.Gong,Y.F.,Zhang,C.S.,Fu,Z.X.,Zhang,W.X.,Li,F.C.and Fang,X.M. (2010). Identification and sequence analysis of MyoG Gene in Boer Goat (Capra hircus). Acta Veterinaria et Zootechnica Sinica., 41(10):1337-1341.
  18. Nabeshima,Y.K.,Hanaoka,A.K.,Hayasaka,M.Esumi,E.,Li ,S.,Nonaka,I. and Nabeshima, Y. (1993). Myogenin gene dismption results in perinatal lethality because of serve muscle defect. Nature., 364(6437):532-535.
  19. Niu, J.J.(2015). Developmental expression of Pax7, MyoD and MyoG genes in longissimus dorsi of pigs. Master’s thesis of Shanxi Agricultural University.
  20. Tepas, M.F.W.,Verburg,F. J.,Gerritsen,C.L.M. and de Greef K. H.(2000). Messenger ribonucleic acid expression of the MyoD gene family in muscle tissue at slaughter in relation to selection for porcine growth rate .Anim Sci.,78(1):69-77.
  21. Wang,Q.,Liu,Y.P.,Jiang,Xiao.Song., Yang,C.W., Du,H.R., Qiu,M.H. and Zhu,M. (2007). Correlation analysis of relationships between polymorphisms of high quality chicken myogenin gene and slaughter and meat quality traits.Hereditas., 29(9):1089-1096.
  22. Wang,W.M.(2018).Genome—wide detection of selection signatures reveals selective imprints of Chinese indigenous sheep breeds during domestication. PhD Dissertation of Huazhong Agricultural University.
  23. Wei,D.W., Ma,X.Y., Zhang,S., Hong,J.Y., Gui,L.S., Mei,C.G., Guo,H.F., Wang,L., Yue- Ning,Y., Zan,L.S.(2017). Characterization of the promoter region of the bovine SIX1 gene: Roles of MyoD, PAX7, CREB and MyoG. Scientific Reports, 7(3): 12599. DOI: 10.1038/ s41598- 017-12787-5.
  24. Wei,Y., Zhang, G.X., Zhang, T., Wang, J.Y., Fan, Q.C., Tang,Y., Ding, F.X. and Zhang, L.(2016). Myf5 and MyoG gene SNPs associated with Bian chicken growth trait. Genetics and Molecular Research, 15 (3): 1-9. DOI: 10.4238/gmr.15037043
  25. Xue,H.L.and Xu,L.X.(2007). A Novel genetic polymorphism and its genetic effects of Porcine Myogenin Gene in Intron 1.Chinese Journal of Biochemistry and Molecuar Biology., 23(8): 612-616.
  26. Yang,M.M.(2014). Genetic analysis of MyoGÿMSTN Gene and construction of MiR-143 Vector in cattle. Master’s Degree Thesis of Anhui Agricultural University.
  27. Zhao,J.,Nie,G.J.,Zhang,J.Z.,Guo,X.L.and Xu,N.Y.(2005). Influences of MyoG gene on reproductive traits in jinhua pig. Hereditas.,    27(6):893-897. 

Editorial Board

View all (0)