Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

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  • Online ISSN 0976-0555

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Indian Journal of Animal Research, volume 54 issue 3 (march 2020) : 349-353

Dose dependent effects of Spirulina Platensis on liver health in rats

Nilay Seyidoglu, Sevda Inan, Nazmiye Gunes
1<div>Tekirdag Namik Kemal University, Faculty of Veterinary,&nbsp;Department of Physiology, Degirmenalti Campus, Suleymanpasa, Tekirdag, Turkey.</div>
Cite article:- Seyidoglu Nilay, Inan Sevda, Gunes Nazmiye (2019). Dose dependent effects of Spirulina Platensis on liver health in rats. Indian Journal of Animal Research. 54(3): 349-353. doi: 10.18805/ijar.B-1055.
Spirulina platensis which is an important microalgae is interested in both human and animal nutrition for health balance. This study’s aimed to evaluate the dose dependent effects of S.platensis on body weight, height, waist circumference (WC), body mass index (BMI), waist/height ratio (WHtR), abdominal fat weight, liver weight, serum liver enzymes and liver histopathology. 30 male Wistar albino rats’re used in groups; Control, SP-1(500mg/kgbw) and SP-2(1000mg/kgbw). S.platensis was administered by oral gavage daily. The body weight, height, WC, BMI, WHtR and abdominal lipid weight were calculated. Also, serum cholesterol, ALT and AST were measured. End of the study, liver tissue samples were taken and scaled and histopathologic changes were recorded. There were no differences in body conditions, but positively significant correlations were found among parameters. As the doses were considered, in groupSP-1, significant positively correlations were determined among abdominal fat, growth, height, BMI and WC statistically. Nevertheless, there were no significant changes in liver weight, serum and histopathologic analyzes. S.platensis with its high concentration of functional nutrients is called as an important alternative therapeutic food and it can be used safely.
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