A study was undertaken to isolate the Staphylococcus sp. Associated sp. Associated with respiratory tract infection in rabbits. In this study isolation, identification and antibiotic susceptibility of the isolates as well as determination of their pathogenicity to mice were carried out. The samples were collected from ailing and dead rabbits. Nasal swabsfrom the ailing rabbits showing clinical signs such as nasal discharge and respiratory distress, tracheal and lung samples of the dead rabbits with postmortem lesions such as pneumonia, congestion of lungs and haemorrhages oftrachea were collected for the isolation trials. A total number of 19 isolates of staphylococci sp. Were obtained. The Staphylococcus sp. thus isolated were Staphylococcus aureus – 11, Staphylococcus scuri-2, Staphylococcus xylosus-1, Staphylococcus intermedius-2, Staphylococcus cohnii-2 and Staphylococcus lentus-1.