EVALUATION OF TRANSAMINASE ACTIVITY OF ETHANOLIC EXTRACT OF FRESH OCIMUM BASILICUM IN RATS

Article Id: ARCC774 | Page : 43- 46
Citation :- EVALUATION OF TRANSAMINASE ACTIVITY OF ETHANOLIC EXTRACT OF FRESH OCIMUM BASILICUM IN RATS.Indian Journal Of Animal Research.2011.(45):43- 46
P.M. Aja and P.N. Onu* nnenwamazi@yahoo.com
Address : Department of Biochemistry and Biotechnology, Ebonyi State University, P M. B. 05 Abakaliki, Ebonyi State, Nigeria.

Abstract

The objective of this study was to evaluate the effects of ethanolic extracts of fresh leaves of Ocimum basilicum on transaminase activities in albino rats. Thirty two male albino rats were randomly assigned to three experimental groups of 12 marked as groups A, B, and C respectively. Groups A and B were treated with oral administration of organic extract of Ocimum basilicum at 400mg and 200mg /kg body weight daily respectively. Group C received no treatment. The body weight of rats of group A and B were significantly (P the body metabolic system and may also elicit a toxic effect especially when taken at high concentration.

Keywords

Albino rats Ethanolic extracts Ocimum basilicum Transaminase activity.

References

  1. Amstrong, J. and King, S. (1954). Amj. Clin. Pattel. 28:26.
  2. Aziba, P. I. et al. (1999). Phytotherapy Res. 13: 427-429.
  3. Cornish, H. H. (1992). CRC.Crit Rev. 1: 32.
  4. Dasgupta, T. et al. (2004). Phytomed. 11: 139-151.
  5. Ezeonu, F.C and Ezejifor, T. I. N. (1998). The Sci. Total Environ. 228: 275-278.
  6. Guenther, E. (1952). In: The Essential oils.: D. Van Nostrad Co., Inc. New York. P. 399-433.
  7. Khan, M.S.H. et al. (2008). Bangl. J. Vet. Med. 6(2):203-210.
  8. Lowry, O. H. (1951). J. Biochem. Int. 193:262-275.
  9. Nelson, D.L. and Cox, M. M. (2000). In: Lehninger Principles of Biochemistry, 3rd Edn, Butter Worth Publishers, London. P. 628-632.
  10. Nsirim, N. (1999). Clinical Biochemistry. 1st Edn, Longman, Nigeria.
  11. Obi I.U. (2002). Statistical Methods of Detecting Differences Between Treatment Means and Research Methodology issue in laboratory and field experiments. A.P Company Ltd.Nigeria.
  12. Okotoro, A. and Ogundele, M. A. (1998). MSc.Thesis .University of Lagos, Nigeria.
  13. Pascul-Villalobos, M. J. and Ballesta-Acosta, M. C. (2003). Biochem. System. and Ecol. 31:673-679.
  14. Ramzi, S. et al. (1999). Medical Pathology, Sixth Edn W.B. Sounders Company.
  15. Salmah, I. et al. (2005). Int. J. Mol. Med. Adv. Sci. 1(3):220-224.
  16. Singh, S. and Majunder, D.K. (1997). Indian J .Exptal Bio. 35:380-383.
  17. Suppakul, P. et al. (2003). J. Agric and Food Chem. 51:3197-3207.
  18. Van, D. and Nguyen, A. (1993). Medicinal plants of Vietnan, Cambodia and Laos, Analysis of essential oils by Gas Chromotography and Mass Spetrometry. John Wiley and Sons Inc. P. 57-61.
  19. Vieira R.F and Simon, J. E. (2000) Economic Botany, 54: 207-216.
  20. Yamasaki, K. et al. (1998). Biol. Pharmacol.Bullietin. 21:829-833.

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