Indian Journal of Animal Research

  • Chief EditorK.M.L. Pathak

  • Print ISSN 0367-6722

  • Online ISSN 0976-0555

  • NAAS Rating 6.50

  • SJR 0.263

  • Impact Factor 0.4 (2024)

Frequency :
Monthly (January, February, March, April, May, June, July, August, September, October, November and December)
Indexing Services :
Science Citation Index Expanded, BIOSIS Preview, ISI Citation Index, Biological Abstracts, Scopus, AGRICOLA, Google Scholar, CrossRef, CAB Abstracting Journals, Chemical Abstracts, Indian Science Abstracts, EBSCO Indexing Services, Index Copernicus
Indian Journal of Animal Research, volume 46 issue 2 (june 2012) : 208 - 209

ASSOCIATION OF GENETIC VARIANTS OF PARTIAL EXON 3 REGION OF TLR4 GENE WITH MASTITIS IN SAHIWAL CATTLE

R.S. Wakchaure, I.D. Gupta*, Archana Verma, Dinesh Kumar1, G.S. Sonawane
1Molecular Genetics Lab, Dairy Cattle Breeding Division, National Dairy Research Institute, Karnal-132 001, India
  • Submitted|

  • First Online |

  • doi

Cite article:- Wakchaure R.S., Gupta* I.D., Verma Archana, Kumar1 Dinesh, Sonawane G.S. (2024). ASSOCIATION OF GENETIC VARIANTS OF PARTIAL EXON 3 REGION OF TLR4 GENE WITH MASTITIS IN SAHIWAL CATTLE. Indian Journal of Animal Research. 46(2): 208 - 209. doi: .
AluI restriction digestion exhibited three AA, AB and BB of partial exon 3 region of TLR4 gene in Sahiwal cattle. It was found that Sahiwal cattle with BB genotype were susceptible (60.00 %) to mastitis. Association between all the genotypes combinations of partial exon 3 region of TLR4 gene was found to be non-significant with mastitis, except between AA and AB genotype.
  1. Falconar, D.S. and Mackay, T.F.C. (1998). Introduction to Quantitative Genetics. 4th edn. Addison Wesley Longman Ltd, Essex, England, pp.1-2.
  2. Godammer T., Zerbe H., Molenaar A., Schuberth H.J., Brunner R.M., Kata S.R., Seyfert H.M. (2004). Mastitis increases mammary mRNA abundance of beta-defensin 5, toll-like-receptor 2 (TLR2), and TLR4 but not TLR9 in cattle. Clin. Diagn. Lab Immunol., 11: 174.
  3. Ogorevc J, Kunej T, Razpet A, Dovc P. (2009). Database of cattle candidate genes and genetic markers for milk production and mastitis. Anim Genet., 40: 832.
  4. Opsal, M.A., Lien S., Brenna-Hansen S., Olsen H.G. and Vage D.I. (2008). Association analysis of the constructed linkage maps covering TLR2 and TLR4 with clinical mastitis in Norwegian Red cattle. J. Anim. Breed.Genet., 125: 110.
  5. Snedecor, G. W. and Cochran, W. G. (1967). Statistical Methods, 8th edition. : State University Press. USA.
  6. Varshney, J.P. and Naresh, R. (2004). Evaluation of homeopathic complex in the clinical management of udder diseases of riverine buffaloes. Homeopathy, 93: 17.
  7. Wang, X.P., Xu, S.Z., Ma, T.H., Gao, X., Ren, H.Y., Chen J.B. (2006). Genetic variation in the 5' flanking region of bovine TLR4 gene and correlation with mastitis. Yi Chuan., 28(12): 1520.
  8. Wang, X., Xu, S., Xue, G., Li, J., Ren, H.and Luoren, Z. (2008). Cloning and SNP screening of the TLR4 gene and the association between its polymorphism and somatic cell score in dairy cattle. South African J. Ani. Sci., 38 (2): 101.

Editorial Board

View all (0)