Indian Journal of Animal Research

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Indian Journal of Animal Research, volume 35 issue 2 (july to december 2001) : 112 - 115

BIOCHEMICAL CHANGES FOLLOWING ULNAR SEGMENTAL DEFECT REPAIR WITH FIBRILLAR COLLAGEN - HYDROXYAPATITE, AND POROUS HYDROXYAPATITE IMPLANTS IN CANINES·

T Madhava Rao\ G.V. Lakshmipathi2, T.P. SastrY, O. Ramakrishna4
1Department of Surgery and Radiology College of Veterinary Science, Tirupati - 517 502, India

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Cite article:- Lakshmipathi2 G.V. Rao\ Madhava T, SastrY T.P., Ramakrishna4 O. (2024). BIOCHEMICAL CHANGES FOLLOWING ULNAR SEGMENTAL DEFECT REPAIR WITH FIBRILLAR COLLAGEN - HYDROXYAPATITE, AND POROUS HYDROXYAPATITE IMPLANTS IN CANINES·. Indian Journal of Animal Research. 35(2): 112 - 115. doi: .

ABSTRACT

In 24 clinically healthy adult mongrel dogs divided into 4 groups of 6 animals each, a transverse middle third diaphyseal segmental defect of 1. 2 cm was created in the ulma. The healing of the gap was evaluated biochemically following repair with autogenous cancellous bone (Group-II), fibrillar collagen-hydroxyapatite composite (Group-III), porous hydroxyapatite (Group-IV). The gap was unfilled in control group (Group-I). The changes in serum calcium, phosphorus and alkaline phosphatase levels were compared with clinical and radiological findings and it is concluded that the fibrillar collagen-hydroxyapatite composite implants can be used as a suitable alternative to the use of autogenous cancellous bone in repair of segmental bone loss defects or non-union fractures.

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