Indian Journal of Animal Research

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Indian Journal of Animal Research, volume 43 issue 2 (june 2009) : 103-106

EVALUATION OF IMMUNOMODULATORY POTENTIAL' OF EMBLICA OFFICINALIS FRUIT PULP EXTRACT IN MICE

R. S. Suja, A. M. C. Nair, S. Sujith, J. Preethy, A. K. Deepa
1College of Veterinary and Animal Sciences (K.A.U.), Mannuthy, 680651, India.

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Cite article:- Suja S. R., Nair C. M. A., Sujith S., Preethy J., Deepa K. A. (2024). EVALUATION OF IMMUNOMODULATORY POTENTIAL' OF EMBLICA OFFICINALIS FRUIT PULP EXTRACT IN MICE. Indian Journal of Animal Research. 43(2): 103-106. doi: .

ABSTRACT

Aqueous extract of dried Emblica officinalis Gaertn. (Amla) fruit pulp powder was evaluated for
immunomodulatory effect on male Swiss Albino mice. The mice were divided into three groups.
The first group received vehicle alone to serve as control. The second and third groups received
the extract orally at 100 and 200 mg! kg body weight dose levels respectively per day for a period
of 19 days. There was significant dose dependent increase in haemagglutination antibody titre,
sheep red blood cells induced delayed type of hypersensitivity reaction, macrophage migration
index, respiratory burst activity of the peritoneal macrophages, total leukocyte count, percentage
lymphocyte distribution, serum globulin and relative lymphoid organ weight in Emblica treated
mice indicating its ability to stimulate humoral as well as cell mediated immunity along with
macrophage phagocyte.

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