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Current IssueEditorial BoardOnline First ArticlesArchive

volume 47 issue 3 (june 2013) : 231-235

COMPARATIVE EFFICACY OF DIFFERENT THERAPEUTIC REGIMES IN THE TREATMENT OF ACUTE BOVINE CLINICAL MASTITIS

Z
Z.A. Akhoon
F
F.U. Peer
K
K.A. Sofi*
1Division of veterinary Medicine, Faculty of Veterinary Sciences and Animal Husbandry, S. K. University of Agricultural Sciences and Technology, Shuhama, Srinagar-190 006, India

  • Submitted|

  • First Online |

  • doi

Cite article:- Akhoon Z.A., Peer F.U., Sofi* K.A. (2025). COMPARATIVE EFFICACY OF DIFFERENT THERAPEUTIC REGIMES IN THE TREATMENT OF ACUTE BOVINE CLINICAL MASTITIS. Indian Journal of Animal Research. 47(3): 231-235. doi: .

ABSTRACT

A therapeutic trial was conducted on cases of acute bovine mastitis. In the therapeutic trial the subgroup I(b) treated with ofloxacin, a recovery rate of 60.67 per cent with mean recovery time of 8 days was observed. In subgroup 1(c) and vitamin ctreated with ofloxacin and vitamin C a recovery rate of 66.67 per cent with a mean recovery time of 7 days was observed. In subgroup I(c) treated with ofloxacin alongwith vitamin E and selenium a recovery rate of 83.33 per cent with a mean recovery time of 6 days was observed. In subgroup II(a), treated with gentamicin alone, a recovery rate of 66.67 per cent with a mean recovery time of 7 days was observed. In subgroup II (b) treated with gentamicin alongwith vitamin C, a recovery rate of 66.67 per cent with a mean recovery time of 6 days was observed. In subgroup II(c) treated with gentamicin alongwith vitamin E and selenium a recovery rate of 83.33 per cent with a mean recovery time of 5 days was observed. The recovery was established by the clinical presentation in terms of swelling, pain, pulse, temperature and milk characteristics. The post-treatment milk chemistry values were significantly different from the pre-treatment values.

REFERENCES

Bendich, A. (1992). Ascorbic acid and immune functions. In: Ascorbic acid in domestic animals (Edd. C. Wenk, R., Fencester and L. Volherl). Institute fur Nutzlierwissen, Chaften Zurich, Switzerland
Bendich, A., Machlin, L.J., Burton, G.W. and Wayner, D.M. 1986. The antioxidant role of vitamin C. Free Rad. Biol. Med. 2 : 419-444.
Erskine, R.J. 1993. Nutrition and mastitis. Vet. Clinical N. Am. Food Ani. Prac. 9 : 551-561.
Goel, P., Kumar, A. And Sharma, A.Therapeutic effects of antioxidants (vitamin E and Selenium) in the mastitic animals. (2005).In : Proceedings of XXIII Annual Convention of ISVM held at COVS and AH., IGAU, Anjora, Durg (CG), February 2-4, 2005, No. 02.
Monicada, S. and Vane, J.R. (1979). Postacyclin. In: The prostaglandin system : Endosperoxides, prostacyclin, and thromboxones (Ed. F. Berti and G.P. Velo). Plenum Press, New York, pp 203-221.
Mukherjee, R. 2007. Selenium and vitamin E increases polymorphonuclear cell phagocytosis and antioxidant levels during acute mastitis in riverine buffaloes. Vet. Res. Com. 32(4) : 305-313.
Ndiweni, N. and Finch, J.M. 1996. Effects of in vitro supplementation with alpha tocopherol and selenium on bovine neutrophils functions : implications for resistance to mastitis. Veterinary Immunology and Immunopathology 51 : 67-68.
Pal, B., Prasad, B. and Nagal, K.B. 1995. Efficacy of trisodium citrate in clinical mastitis in cows. Indian Veterinary Journal 1 : 71-74.
Peterrkofsky, B. 1991. Ascorbate requirement for hydroxylation and secretion of procollagen; relationship to inhibition of collagen synthesis in scurvy. American J. Clin. Nut. 54 : 1135-1140.
Politis, I., Hidiroglou, N., White, J.H., Gilmore, J.A., Williams, S.N., Scherf, H. and Frigg, M. 1996. Effect of vitamin E on mammary and blood leukocyte function with emphasis on chemotaxis, in periparturient dairy cows. American J. Vet. Resear Ranjan, R., Swarup, D., Ram, N. and Patra, R.C. 2005. Ameliorative potential of L-ascorbic acid in bovine clinical mastitis. Indian Journal of Animal Sciences 75(2) : 174-177.
Ranjan, R., Swarup, D., Ram, N. and Patra, R.C. 2005. Ameliorative potential of L-ascorbic acid in bovine clinical mastitis. Indian Journal of Animal Sciences 75(2) : 174-177.
Saluja, P.S. (1999).Studies on bovine mastitis with special reference to management practices and its therapeutic control. Ph.D thesis submitted to CCS Haryana Agri. Univ., Hisar, India
Sandholm, M., Kaartinen, L. and Pyoala, S. 1990. Bovine mastitis – why does antibiotic theraphy not always work. An overview. J. Vet. Pharmacol. Therap. 13 : 248.
Sharma, N., Maiti, S.K. and Gupta, S.K. (2006).Effect of dietary supplementation of vitamin E and Selenium in sub- clinical mastitis in dairy cattle. In: Proceedings of National Conference of ISVM, held at Veterinary College, Bangalore, February 2006, p. 4.
Singh, H., Kirti, Dua, Randhawa, S.S. and Uppal, S.K. 2000. Role of vitamin E and selenium in the treatment of clinical mastitis. Ind. J. Vet. Medicine 20(2) : 59-60.
Singh, P.J. and Singh, P.B. 1994. A study on economic losses due to mastitis in India. Ind. J. Dairy Sci.47(4) : 265-272.
Singh, S.V. and Pachauri, S.P. 2003. Milk ascorbic acid concentration in normal and mastitic cows. Indian J. Vet. Medicine. 2 : 88-89.
Smith, K.L., Harrison, J.H., Hamcock, D.D., Todhunter, D.A. and Conrad, H.R. 1984. Effect of vitamin E and selenium supplementation on incidence of clinical mastitis and duration of clinical symptoms. J. Dairy Sci. 67 : 1293-1300.
Snedecor, G W and Cochran, W G (1989). Statistical Methods. 8th edition. Iowa State Univ. Press, Ames, Iowa, USA.
Upadhay, A.K. and Dwivedi, H.P. 2004. Effect of mineral supplementation in mastitic cows. Indian Vet. Journal 81 : 1061-1062.
Weiss, W.P., Hogan, D.A., Todhunter, D.A. and Smith, K.L. 1997. Effect of vitamin E supplementation in diets with a low concentration of selenium on mammary gland health of dairy cows. J. Dairy Sci. 80 : 1728-1737.
Weiss, W.P., Hogan, J.S. and Smith, K.L. 2004. Changes in vitamin C concentration in plasma and milk from dairy cows after an intramammary infusion of Escherichia coli. J. Dairy Sci. 87 : 32-37.


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    volume 47 issue 3 (june 2013) : 231-235

    COMPARATIVE EFFICACY OF DIFFERENT THERAPEUTIC REGIMES IN THE TREATMENT OF ACUTE BOVINE CLINICAL MASTITIS

    Z
    Z.A. Akhoon
    F
    F.U. Peer
    K
    K.A. Sofi*
    1Division of veterinary Medicine, Faculty of Veterinary Sciences and Animal Husbandry, S. K. University of Agricultural Sciences and Technology, Shuhama, Srinagar-190 006, India

    • Submitted|

    • First Online |

    • doi

    Cite article:- Akhoon Z.A., Peer F.U., Sofi* K.A. (2025). COMPARATIVE EFFICACY OF DIFFERENT THERAPEUTIC REGIMES IN THE TREATMENT OF ACUTE BOVINE CLINICAL MASTITIS. Indian Journal of Animal Research. 47(3): 231-235. doi: .

    ABSTRACT

    A therapeutic trial was conducted on cases of acute bovine mastitis. In the therapeutic trial the subgroup I(b) treated with ofloxacin, a recovery rate of 60.67 per cent with mean recovery time of 8 days was observed. In subgroup 1(c) and vitamin ctreated with ofloxacin and vitamin C a recovery rate of 66.67 per cent with a mean recovery time of 7 days was observed. In subgroup I(c) treated with ofloxacin alongwith vitamin E and selenium a recovery rate of 83.33 per cent with a mean recovery time of 6 days was observed. In subgroup II(a), treated with gentamicin alone, a recovery rate of 66.67 per cent with a mean recovery time of 7 days was observed. In subgroup II (b) treated with gentamicin alongwith vitamin C, a recovery rate of 66.67 per cent with a mean recovery time of 6 days was observed. In subgroup II(c) treated with gentamicin alongwith vitamin E and selenium a recovery rate of 83.33 per cent with a mean recovery time of 5 days was observed. The recovery was established by the clinical presentation in terms of swelling, pain, pulse, temperature and milk characteristics. The post-treatment milk chemistry values were significantly different from the pre-treatment values.

    REFERENCES

    Bendich, A. (1992). Ascorbic acid and immune functions. In: Ascorbic acid in domestic animals (Edd. C. Wenk, R., Fencester and L. Volherl). Institute fur Nutzlierwissen, Chaften Zurich, Switzerland
    Bendich, A., Machlin, L.J., Burton, G.W. and Wayner, D.M. 1986. The antioxidant role of vitamin C. Free Rad. Biol. Med. 2 : 419-444.
    Erskine, R.J. 1993. Nutrition and mastitis. Vet. Clinical N. Am. Food Ani. Prac. 9 : 551-561.
    Goel, P., Kumar, A. And Sharma, A.Therapeutic effects of antioxidants (vitamin E and Selenium) in the mastitic animals. (2005).In : Proceedings of XXIII Annual Convention of ISVM held at COVS and AH., IGAU, Anjora, Durg (CG), February 2-4, 2005, No. 02.
    Monicada, S. and Vane, J.R. (1979). Postacyclin. In: The prostaglandin system : Endosperoxides, prostacyclin, and thromboxones (Ed. F. Berti and G.P. Velo). Plenum Press, New York, pp 203-221.
    Mukherjee, R. 2007. Selenium and vitamin E increases polymorphonuclear cell phagocytosis and antioxidant levels during acute mastitis in riverine buffaloes. Vet. Res. Com. 32(4) : 305-313.
    Ndiweni, N. and Finch, J.M. 1996. Effects of in vitro supplementation with alpha tocopherol and selenium on bovine neutrophils functions : implications for resistance to mastitis. Veterinary Immunology and Immunopathology 51 : 67-68.
    Pal, B., Prasad, B. and Nagal, K.B. 1995. Efficacy of trisodium citrate in clinical mastitis in cows. Indian Veterinary Journal 1 : 71-74.
    Peterrkofsky, B. 1991. Ascorbate requirement for hydroxylation and secretion of procollagen; relationship to inhibition of collagen synthesis in scurvy. American J. Clin. Nut. 54 : 1135-1140.
    Politis, I., Hidiroglou, N., White, J.H., Gilmore, J.A., Williams, S.N., Scherf, H. and Frigg, M. 1996. Effect of vitamin E on mammary and blood leukocyte function with emphasis on chemotaxis, in periparturient dairy cows. American J. Vet. Resear Ranjan, R., Swarup, D., Ram, N. and Patra, R.C. 2005. Ameliorative potential of L-ascorbic acid in bovine clinical mastitis. Indian Journal of Animal Sciences 75(2) : 174-177.
    Ranjan, R., Swarup, D., Ram, N. and Patra, R.C. 2005. Ameliorative potential of L-ascorbic acid in bovine clinical mastitis. Indian Journal of Animal Sciences 75(2) : 174-177.
    Saluja, P.S. (1999).Studies on bovine mastitis with special reference to management practices and its therapeutic control. Ph.D thesis submitted to CCS Haryana Agri. Univ., Hisar, India
    Sandholm, M., Kaartinen, L. and Pyoala, S. 1990. Bovine mastitis – why does antibiotic theraphy not always work. An overview. J. Vet. Pharmacol. Therap. 13 : 248.
    Sharma, N., Maiti, S.K. and Gupta, S.K. (2006).Effect of dietary supplementation of vitamin E and Selenium in sub- clinical mastitis in dairy cattle. In: Proceedings of National Conference of ISVM, held at Veterinary College, Bangalore, February 2006, p. 4.
    Singh, H., Kirti, Dua, Randhawa, S.S. and Uppal, S.K. 2000. Role of vitamin E and selenium in the treatment of clinical mastitis. Ind. J. Vet. Medicine 20(2) : 59-60.
    Singh, P.J. and Singh, P.B. 1994. A study on economic losses due to mastitis in India. Ind. J. Dairy Sci.47(4) : 265-272.
    Singh, S.V. and Pachauri, S.P. 2003. Milk ascorbic acid concentration in normal and mastitic cows. Indian J. Vet. Medicine. 2 : 88-89.
    Smith, K.L., Harrison, J.H., Hamcock, D.D., Todhunter, D.A. and Conrad, H.R. 1984. Effect of vitamin E and selenium supplementation on incidence of clinical mastitis and duration of clinical symptoms. J. Dairy Sci. 67 : 1293-1300.
    Snedecor, G W and Cochran, W G (1989). Statistical Methods. 8th edition. Iowa State Univ. Press, Ames, Iowa, USA.
    Upadhay, A.K. and Dwivedi, H.P. 2004. Effect of mineral supplementation in mastitic cows. Indian Vet. Journal 81 : 1061-1062.
    Weiss, W.P., Hogan, D.A., Todhunter, D.A. and Smith, K.L. 1997. Effect of vitamin E supplementation in diets with a low concentration of selenium on mammary gland health of dairy cows. J. Dairy Sci. 80 : 1728-1737.
    Weiss, W.P., Hogan, J.S. and Smith, K.L. 2004. Changes in vitamin C concentration in plasma and milk from dairy cows after an intramammary infusion of Escherichia coli. J. Dairy Sci. 87 : 32-37.


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